Nonsteroidal is a term used to describe a compound that is not a steroid and to indicate as such.
It is used in the name of nonsteroidal anti-inflammatory drugs (NSAIDs) to distinguish them from corticosteroids as a class of anti-inflammatory agents.
Nonsteroidal is also used to describe steroidergic drugs that are not steroid derivatives. Examples include the following:
Estrogens: benzestrol, bifluranol, DBE, diethylstilbestrol (stilbestrol), dienestrol, fosfestrol, hexestrol (dihydroxystilbestrol), methallenestril, methestrol, methestrol dipropionate, paroxypropione, prinaberel, and triphenylethylene, as well as many xenoestrogens
SERMs: acolbifene, afimoxifene, arzoxifene, bazedoxifene, broparestrol, chlorotrianisene, clomifene, clomifenoxide, cyclofenil, droloxifene, enclomifene, endoxifen, ethamoxytriphetol, fispemifene, idoxifene, lasofoxifene, levormeloxifene, miproxifene, nafoxidine, nitromifene, ormeloxifene, ospemifene, panomifene, pipendoxifene, raloxifene, sivifene, tamoxifen, tesmilifene, toremifene, trioxifene, zindoxifene, zuclomifene
Antiandrogens: apalutamide, bicalutamide, cimetidine, darolutamide, DIMP, enzalutamide, EPI-001, EPI-506, flutamide, hydroxyflutamide, inocoterone, ketoconazole, nilutamide, orteronel, RU-58642, RU-58841, and topilutamide
SARMs: AC-262,356, acetothiolutamide, andarine, BMS-564,929, enobosarm (ostarine), GW-501516, JNJ-28330835, LGD-2226, LGD-3303, LGD-4033, S-23, and S-40503
Miscellaneous: tanaproget (progestogen), finerenone (antimineralocorticoid), esaxerenone (antimineralocorticoid), apararenone (antimineralocorticoid), AZD5423 (glucocorticoid), AL082D06 (antiglucocorticoid), mapracorat (SGRM), and Org 214007-0 (SGRM)
