Rahul Sharma (Editor)

Hydroxyflutamide

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CAS Number
  
52806-53-8

IUPHAR/BPS
  
2862

UNII
  
31D90UKP5Y

PubChem CID
  
91649

ChemSpider
  
82752

Molar mass
  
292.2112 g/mol

Hydroxyflutamide wwwsigmaaldrichcomcontentdamsigmaaldrichstr

Synonyms
  
Hydroxyniphtholide, hydroxyniftolide; α,α,α-trifluoro-2-methyl-4'-nitro-m-lactotoluidide

Hydroxyflutamide (HF, OHF) (developmental code name SCH-16423), or 2-hydroxyflutamide, is a non-steroidal antiandrogen. It is the major active metabolite of flutamide. It is reported to possess an IC50 of 700 nM for the androgen receptor (AR), about 4-fold less than that of bicalutamide.

References

Hydroxyflutamide Wikipedia