Symbol BRCT InterPro IPR001357 SUPERFAMILY 1cdz | Pfam PF00533 SCOP 1cdz CDD cd00027 | |
![]() | ||
BRCA1 C Terminus (BRCT) domain is a family of evolutionarily related proteins.
The BRCT domain (after the C_terminal domain of a breast cancer susceptibility protein) is found predominantly in proteins involved in cell cycle checkpoint functions responsive to DNA damage, for example as found in the breast cancer DNA-repair protein BRCA1. The domain is an approximately 100 amino acid tandem repeat, which appears to act as a phospho-protein binding domain.
Examples
Human proteins containing this domain include:
References
BRCT domain Wikipedia(Text) CC BY-SA