Species Human Entrez 23481 | Human Mouse Ensembl ENSG00000100029 | |
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Aliases PES1, PES, pescadillo ribosomal biogenesis factor 1 External IDs MGI: 1890613 HomoloGene: 5984 GeneCards: PES1 | ||
Pescadillo homolog is a protein that in humans is encoded by the PES1 gene.
This gene encodes a protein that is abnormally elevated in malignant tumors of astrocytic origin. It is a strongly conserved gene containing a BRCT domain that is essential for the activity of this gene product. The gene plays a crucial role in cell proliferation and may be necessary for oncogenic transformation and tumor progression.
References
PES1 Wikipedia(Text) CC BY-SA