Entrez 22976 | Ensembl ENSG00000157212 | |
 | ||
External IDs HomoloGene: 133914 GeneCards: PAXIP1 | ||
PAX-interacting protein 1 is a protein that in humans is encoded by the PAXIP1 gene.
Contents
Function
This gene is a member of the paired box (PAX) gene family and encodes a nuclear protein with six BRCT (breast cancer carboxy-terminal) domains. This protein plays a critical role in maintaining genome stability, condensation of chromatin and progression through mitosis. Protein-affecting variants have also been implicated in Alzheimer's disease.
Interactions
References
PAXIP1 Wikipedia(Text) CC BY-SA