Species Human Entrez 1894 | Human Mouse Ensembl ENSG00000114346 | |
 | ||
Aliases ECT2, ARHGEF31, epithelial cell transforming 2 External IDs MGI: 95281 HomoloGene: 7298 GeneCards: ECT2 | ||
Protein ECT2 is a protein that in humans is encoded by the ECT2 gene.
Contents
Function
The protein encoded by this gene is a transforming protein that is related to Rho-specific exchange factors and yeast cell cycle regulators. The expression of this gene is elevated with the onset of DNA synthesis and remains elevated during G2 and M phases. In situ hybridization analysis showed that expression is at a high level in cells undergoing mitosis in regenerating liver. Thus, this protein is expressed in a cell cycle-dependent manner during liver regeneration, and is thought to have an important role in the regulation of cytokinesis.
Interactions
ECT2 has been shown to interact with PARD6A.
References
ECT2 Wikipedia(Text) CC BY-SA