Samiksha Jaiswal (Editor)

Transmembrane domain of ABC transporters

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Symbol
  
ABC_membrane

InterPro
  
IPR001140

SCOP
  
1pf4

Pfam
  
PF00664

PROSITE
  
PDOC00364

SUPERFAMILY
  
1pf4

ABC transporter transmembrane domain is the main transmembrane structural unit of ATP-binding cassette transporter proteins, consisting of six alpha helix transmembrane domains which traverse the plasma membrane. Many members of the ABC transporter family (Pfam PF00005) have two such regions.

Contents

Subfamilies

  • Sulphate ABC transporter permease protein 2 InterPro: IPR005667
  • Phosphate transport system permease protein 2 InterPro: IPR005672
  • Phosphonate uptake transporter InterPro: IPR005769
  • Nitrate transport permease InterPro: IPR005889
  • NifC-like ABC-type porter InterPro: IPR006469
  • Phosphate ABC transporter, permease protein PstC InterPro: IPR011864
  • Molybdate ABC transporter, permease protein InterPro: IPR011867
  • Nickel ABC transporter, permease subunit NikB InterPro: IPR014156
  • Nickel ABC transporter, permease subunit NikC InterPro: IPR014157
  • Ectoine/hydroxyectoine ABC transporter, permease protein EhuD InterPro: IPR014341
  • Ectoine/hydroxyectoine ABC transporter, permease protein EhuC InterPro: IPR014342

    • Human proteins containing this domain

    ABCB1; ABCB10; ABCB11; ABCB4; ABCB5; ABCB6; ABCB7; ABCB8; ABCB9; ABCC1; ABCC10; ABCC11; ABCC12; ABCC13; ABCC2; ABCC3; ABCC4; ABCC5; ABCC6; ABCC8; ABCC9; CFTR; TAP1; TAP2; TAPL;

    References

    Transmembrane domain of ABC transporters Wikipedia
    (Text) CC BY-SA


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