1803 – David Collins sent from Sydney to establish a settlement for the British Government. Unaware of previous discoveries, Collins settles near present-day Sullivan Bay on the Mornington Peninsula. This settlement is abandoned five months later.
1834 – Henty family establish first long-term European settlement in Victoria at Portland
1835 – John Batman sails to the mouth of the Yarra from Tasmania in the Rebecca
1835 – John Batman 'buys' the 2,430 km² that Melbourne would be founded on from the local Aboriginal nation, the Wurundjeri. The Batman Deed is now widely recognised to be more of a treaty than a sale.
1835 – Melbourne is founded by John Batman and John Pascoe Fawkner
1836 – William Lonsdale built the first government block, declaring Melbourne the capital of the Port Phillip district
1837 – 28 March - Hoddle Grid of streets for the central business district is surveyed by Robert Hoddle
1837 – 1 June – First inner-city land sale
1838 – Melbourne is declared a legal port and administrative centre, opening the way for vastly increased immigration
1854 – First steam railway journey in Australia from Melbourne Terminus (on the current site of Flinders Street station) to Sandridge (later Port Melbourne)
1854 – Melbourne Exhibition held in conjunction with Exposition Universelle (1855)
1878 – Xavier College, in Kew, is founded after the increased need of boarding space for the oldest Jesuit School in Melbourne, St Pat's.
1878 – Ruyton Girls' School, also in Kew is founded by Charlotte Anderson. Its land includes the heritage listed Henty House, built by the seminal Hentys of Sussex.
1957 – Plot ratio height limits introduced to CBD (dependent upon floor space and light angles), plazas and open space. By laws introduced for compulsory carspace for all new city buildings. 1.45 m setbacks for 'Little' streets introduced to widen footpaths.
2002 – Controversial Melbourne 2030 planning policy introduced, aimed to increase population in designated 'activity centres' and curb urban sprawl, promises to increase public transport usage to 20% of motorised trips by 2020