The film, which was set in the backdrop of news media, has Mohanlal playing the role of a channel cameraman Venu and Amala Paul that of a senior editor Renuka. The story traces their relationship and professional conflicts. It released worldwide on 29 August 2012. The film was one of the highest grossed Malayalam film of 2012.
Venu (Mohanlal) is a high-profile news cameraman working in Reuters. He graduated from a premier film institute but preferred to shoot news rather than the manipulated visuals for movies. He is mostly based in Delhi but has come to Kochi to appear for a case in which he is involved. He is assigned to cover a case involving a local politician where he gets to meet Renuka (Amala Paul). Renuka is the executive editor of Bharath Vision and Venu and Renuka have a story to tell of their own. A flashback tells the story about how two lovers turned into foes.
Rishikesh (Biju Menon) is another channel head NBI ((News Bureau of India)), who is going through some difficult times, as some of his star performers have gone in search of greener pastures. Venu and Renuka come together to investigate a particular story about a murder planned by Bharathan Pillai (Sai Kumar), a major politician who had lost his fame and name before many years when Venu and Renuka exposed a scam involving him.Mohanlal as Venu
Amala Paul as Renuka
Biju Menon as Hrishikesh
Aparna Nair as Indu Panicker
Ameer Niyaz as Abu
Sai Kumar as Bharathan Pillai
Siddique as Rajan Kartha
Krishna Kumar as Vijaya Kumar
Shammi Thilakan as D.Y.S.P Benny
Mithun Ramesh as Advocate Manilal
Anil Murali as Sugunan
Joju George as Shibu
Jins Varghese as Sanju (Sub editor of Renuka)
Sivaji Guruvayoor as Minister Kunjali
The film is produced by Milan Jaleel under the banner of Galaxy Films. Cinematography was done by R. D. Rajasekhar and music direction by Ratheesh Vegha. Stills were done by Aaghosh.
Run Baby Run was written by Sachy.
Mohanlal held a sneak preview of the film on 28 August, at a theatre owned by director Priyadarshan in Chennai. The preview was attended by Amala Paul, Priyadarsan, Suresh Balaji, Lizzy Priyadarsan, Ouseppachan, and R. D. Rajasekhar.
Paresh C Palicha of Rediff.com wrote, "The acting department depends on Mohanlal a bit too much", but described Mohanlal's performance as "impeccable". IbnLive.in called it as a "gripping thriller" lauding Mohanlal's performance, script, direction and technicians said "the film is a roller coaster ride. The movie has the precise doses of actions, thrills, lighter moments and finer sequences which are also laced with a fine performance of the cast" and concluded "For the lovers of relatively well made thrillers, 'Run baby Run' is definitely your movie and you may love to see it, more than once. Forget the little glitches and watch the wonderful performance of Mohanlal.".
Oneindia.in praised Mohanlal's performance as "outstanding" and complimented RD Rajasekhar's cinematography. Sify.com rated it as "Very Good" and said that "Run Babby Run is a thriller that keeps you glued on to the screens. It is a gripping tale with some good visuals and excellent performances. On the whole it is an engaging thriller which has the right doses of histrionics, tautness, anguish and thrills."
G. Krishnamurthy of Indulekha.com said "Run baby Run is the only Malayalam film released which can be recommended to watch among the Onam releases.". Giving special mention to Mohanlal, Sachy, Joshiy, R.D Rajasekhar and other creative department. Unni R Nair of Kerala9.com rated 3/5 and stated "Joshiy is in full control. As usual, he has done full justice to the subject at hand and has delivered perfectly well." and with a praise for performance and technical aspects.
Raj Vikram of Metro Matinee gave a verdict "Run baby Run entertains" and concluded "In spite of all the faults, “Run Babby Run” manages to run and reach home mainly because of the overwhelming presence of Mohanlal who comes out with another mesmerizing performance. At times, the flick turns to a fine entertainer for this festival season even by leaving few down points.". Ashwin j Kumar of The Times of India rated 3/5 and said "The film depicts the true face of media war. The film is driven by a flimsy narrative and lavished with twists."
The film grossed nearly ₹15 crore (US$2.3 million) from theatres. '
The soundtrack was composed by Ratheesh Vegha, with lyrics penned by Rafeeq Ahmed. Mohanlal sings a folk number titled "Attumanal Payayil" in this film. The album consists of six songs. The audio rights were acquired by Manorama Music for a price of ₹16 million (US$250,000). The album was launched on 25 August 2012 at Dream Hotel in Kochi. The event was attended by Mohanlal, Mammootty, Joshiy, Mukesh, Milan Jaleel, Ratheesh Vegha, Amala Paul and several personalities from the film industry along with the technical crew and cast of Run Baby Run.