Supriya Ghosh (Editor)

Hematologic disease

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MeSH
  
D006402

Hematologic diseases are disorders which primarily affect the blood. Hematology includes the study of these disorders.

Contents

Myeloid

  • Hemoglobinopathies (congenital abnormality of the hemoglobin molecule or of the rate of hemoglobin synthesis)
  • Sickle-cell disease
  • Thalassemia
  • Methemoglobinemia
  • Anemias (lack of red blood cells or hemoglobin)
  • Iron deficiency anemia
  • Megaloblastic anemia
  • Vitamin B12 deficiency
  • Pernicious anemia
  • Folate deficiency
  • Hemolytic anemias (destruction of red blood cells)
  • Genetic disorders of RBC membrane
  • Hereditary spherocytosis
  • Hereditary elliptocytosis
  • Congenital dyserythropoietic anemia
  • Genetic disorders of RBC metabolism
  • Glucose-6-phosphate dehydrogenase deficiency (G6PD)
  • Pyruvate kinase deficiency
  • Immune mediated hemolytic anemia (direct Coombs test is positive)
  • Autoimmune hemolytic anemia
  • Warm antibody autoimmune hemolytic anemia
  • Idiopathic
  • Systemic lupus erythematosus (SLE)
  • Evans' syndrome (antiplatelet antibodies and hemolytic antibodies)
  • Cold autoimmune hemolytic anemia
  • Cold agglutinin disease
  • Paroxysmal cold hemoglobinuria (rare)
  • Infectious mononucleosis
  • Alloimmune hemolytic anemia
  • Hemolytic disease of the newborn (HDN)
  • Rh disease (Rh D)
  • ABO hemolytic disease of the newborn
  • Anti-Kell hemolytic disease of the newborn
  • Rhesus c hemolytic disease of the newborn
  • Rhesus E hemolytic disease of the newborn
  • Other blood group incompatibility (RhC, Rhe, Kid, Duffy, MN, P and others)
  • Drug induced immune mediated hemolytic anemia
  • Penicillin (high dose)
  • Methyldopa
  • Hemoglobinopathies (where these is an unstable or crystalline hemoglobin)
  • Paroxysmal nocturnal hemoglobinuria (rare acquired clonal disorder of red blood cell surface proteins)
  • Direct physical damage to RBCs
  • Microangiopathic hemolytic anemia
  • Secondary to artificial heart valve(s)
  • Aplastic anemia
  • Fanconi anemia
  • Diamond-Blackfan anemia (inherited pure red cell aplasia)
  • Acquired pure red cell aplasia
  • Decreased numbers of cells
  • Myelodysplastic syndrome
  • Myelofibrosis
  • Neutropenia (decrease in the number of neutrophils)
  • Agranulocytosis
  • Glanzmann's thrombasthenia
  • Thrombocytopenia (decrease in the number of platelets)
  • Idiopathic thrombocytopenic purpura (ITP)
  • Thrombotic thrombocytopenic purpura (TTP)
  • Heparin-induced thrombocytopenia (HIT)
  • Myeloproliferative disorders (Increased numbers of cells)
  • Polycythemia vera (increase in the number of cells in general)
  • Erythrocytosis (increase in the number of red blood cells)
  • Leukocytosis (increase in the number of white blood cells)
  • Thrombocytosis (increase in the number of platelets)
  • Myeloproliferative disorder
  • Coagulopathies (disorders of bleeding and coagulation)
  • Thrombocytosis
  • Recurrent thrombosis
  • Disseminated intravascular coagulation
  • Disorders of clotting proteins
  • Hemophilia
  • Hemophilia A
  • Hemophilia B (also known as Christmas disease)
  • Hemophilia C
  • Von Willebrand disease
  • Disseminated intravascular coagulation
  • Protein S deficiency
  • Antiphospholipid syndrome
  • Disorders of platelets
  • Thrombocytopenia
  • Glanzmann's thrombasthenia
  • Wiskott-Aldrich syndrome

    • Hematological malignancies

  • Hematological malignancies
  • Lymphomas
  • Hodgkin's disease
  • Non-Hodgkin's lymphoma {includes the next five entries}
  • Burkitt's lymphoma
  • Anaplastic large cell lymphoma
  • Splenic marginal zone lymphoma
  • Hepatosplenic T-cell lymphoma
  • Angioimmunoblastic T-cell lymphoma (AILT)
  • Myelomas
  • Multiple myeloma
  • Waldenström macroglobulinemia
  • Plasmacytoma
  • Leukemias increased WBC
  • Acute lymphocytic leukemia (ALL)
  • Chronic lymphocytic leukemia (CLL){now included in theCLL/SCLL type NHL}
  • Acute myelogenous leukemia (AML)
  • Chronic Idiopathic Myelofibrosis (MF)
  • Chronic myelogenous leukemia (CML)
  • T-cell prolymphocytic leukemia (T-PLL)
  • B-cell prolymphocytic leukemia (B-PLL)
  • Chronic neutrophilic leukemia (CNL)
  • Hairy cell leukemia (HCL)
  • T-cell large granular lymphocyte leukemia (T-LGL)
  • Aggressive NK-cell leukemia

    • Miscellaneous

  • Hemochromatosis
  • Asplenia
  • Hypersplenism
  • Gaucher's disease
  • Monoclonal gammopathy of undetermined significance
  • Hemophagocytic lymphohistiocytosis
  • Tempi syndrome

    • Hematological changes secondary to non-hematological disorders

  • Anemia of chronic disease
  • Infectious mononucleosis
  • AIDS
  • Malaria
  • Leishmaniasis

    • References

    Hematologic disease Wikipedia
    (Text) CC BY-SA