The film is broken into three chapters centred around three men (all played by Ryan Reynolds) who try to uncover the secret about strange happenings in their, at times overlapping, lives.
Gary is a troubled actor who is wearing a green bracelet on his wrist, under house arrest living in another person's house because he burned down his own. The owner of the house is described as a TV writer away on work. While living in the house he is befriended by both a P.R. 'handler', Margaret, and the single mom next door, Sarah, who may or may not be interested in him romantically. Over the course of his house arrest, Gary becomes convinced that he is being haunted by the number nine, including finding a note saying "Look for the nines" in his handwriting. He encounters many occurrences of the number nine, while playing backgammon he rolls nines, while reading newspaper advertisements he becomes obsessed with finding nines. Asking Sarah about the number 9 worries her and she cryptically tells him "I can get you out of here". He also sees different versions of himself around the house, which unsettles him, causing him to break out of his house arrest barrier, which in turn causes a blip in reality.
A television writer, Gavin, trying to get his pilot produced. He leaves home to work on his TV show, Knowing, about a mother and daughter who are lost, which stars his friend Melissa as the lead actress. In a conversation about reviews and critics Susan, a television executive and producer of the show, tells Gavin to look for the nines which he then writes on a piece of paper, the same piece which Gary found in Part One. He also tells Melissa he thinks he is haunted by himself. During the process of post production, Susan pushes for Gavin to ditch his friend Melissa as the unconventional lead of his project in favor of a more attractive, well-known actress. This causes an argument between him and Melissa. He then finds out that the well-known actress was actually cast in another show which Susan knew of before suggesting her. Since she is now unavailable and Melissa won't answer Gavin's calls, he confronts Susan about her knowing his show would never get picked up and about him only being a subject on a reality television show. After a heated exchange, he snaps and slaps her. Insulting his manhood for hitting a woman, she scoffs "Do you think you are a man?" and walks away, which leads to him telling the reality TV cameraman to leave him alone. A pedestrian then asks him who he is talking to, and it is shown that the reality television cameraman does not exist. He looks around and notices that everyone has a 7 floating above their heads and also that he has a 9 floating above his head.
A flashback shows Gary's P.R. handler, Margaret, telling him he is a God-like being and that God is a 10, humans are a 7 and that he is a 9 (koalas, incidentally, are 8s because they control weather), therefore he can destroy the world with a single thought, and that he exists in many different forms and that none of them are real. Gary does not believe this and flips out, which is revealed to be the real reason for his breaking his house arrest barrier.
Acclaimed video game designer Gabriel, whose car breaks down in the middle of nowhere, leaves his wife, Mary, and young daughter, Noelle, to try to get a better signal on his phone. He meets a woman, Sierra (Davis), who leads him off into the woods to her car, so she can give him a lift to the gas station. Meanwhile, back at the car Noelle watches a video on a digital camera showing Gavin talking to Melissa from Part Two and Margaret talking to Gary in Part One. She is confused and shows her mom, who appears confused as well.
Meanwhile, Gabriel shows signs of intoxication, as Sierra had drugged water she was giving him with GHB. She has been trying all along as Sarah, Sierra, Susan to separate the other three incarnations of "G" from Mary. That poisoning him with GHB was the only way to get him to stop long enough to reason with him. She calms Gabriel by telling him that this is an intervention and they (the Prostitute from part 1, and parole officer/agitated man), were trying to help him come home. She likens Gabriel's addiction to video game addiction. That Gabriel has been playing for 4,000 years reincarnating into different roles to play with the humans. The 3 nines plead with him to come back home.
Back at the car, Noelle has gone missing. Gabriel then returns to the car with Noelle in his arms and the family goes home. Mary, who realizes that he is not who he seems, tells Gabriel he needs to go and that the world is not real. Gabriel tells her that there were ninety different variations of the universe and this is the last one. Gabriel then realizes he must go and removes the green bracelet from his wrist, at which point the universe peels away into nothing. The film ends with the woman from all three parts married to Ben, whom she is married to in Part Two, and Noelle as their daughter. Noelle tells her mother that "he's not coming back" and that "all the pieces have been put together" and her mother finishes her sentence that this is "the best of all possible worlds."Ryan Reynolds as a niner named: "G", Gary a troubled actor/ Gavin a TV writer/ and Gabriel a Computer-Game designer
Melissa McCarthy as Margaret, Gary's PR handler/ Melissa an actress in Gavin's TV show/ and Mary, Gabriel's wife.
Hope Davis as a niner presumably named "S" Sarah, Gary's Neighbor/ Susan a TV executive for Gavin/ and Sierra a mysterious woman who tries to help Gabriel
Elle Fanning as Noelle
David Denman as Parole Officer / Agitated Man / Nine
Octavia Spencer as Streetwalker (credited) / Pedestrian (uncredited) / Nine
The movie was shot over 22 days in Los Angeles and two days in New York, with some scenes in John August's house. The movie was shot in a combination of video and film with everything being posted in high-definition."You Keep Me Hangin' On" Performed by The Ferris Wheel (band)
"Trucha" Performed by Ghostman MC
"Alive Transmission" Performed by The Shys
"Hang On Little Tomata" Performed by Pink Martini
"Is That All There Is" Performed by Hope Davis
"Paper Plane" Performed by Persephone's Bees
"Teenage Villain" Written by Keith Mansfield
"Bang Bang To The Rock 'N' Roll" Performed by Gabin
"Comet Samba" Performed by Cabaret Diosa
"Monokini Ou Bikini" Performed by Georges Deligny
"Romantico Bosanova" Written by Philippe Bestion
"As Long As He Needs Me" Performed by Melissa McCarthy
"Multiply" Performed by Jamie Lidell
"Sugar Town" Performed by Juliet Turner
"Myopia" Performed by The Skeem
"Tears Coming Home" Performed by Sebastien Schuller
"Chopin Nocturne 1, Opus 32" Performed by Danielle Luppi
"The Other Side Of Mt. Heart Attack" Performed by Liars
"The Finish Line" Performed by Snow Patrol
Overall critical reception to the film has been mixed. The film currently holds a 64% "Fresh" approval rating on Rotten Tomatoes, with an average critical rating of 5.9/10, while holding a 62% approval rating from audiences, with an average audience score of 6.6/10. On Metacritic, the film holds a meta-score of 52/100, indicating mixed or average reviews, based on 12 critical reviews: 6 positive, 3 mixed, and 3 negative. However, Metacritic's user reviews indicate generally favorable reviews, with a meta-score of 69/100, based on 31 reviews.34th Saturn Awards
Nomination:Best DVD release