Kandpal was born in a Kumauni Brahman family in Nainital, Uttarakhand to Mr. and Mrs. B.D Kandpal. She has two siblings, an elder sister Bhavna Kandpal and a younger brother Manjul Kandpal. During her growing up days, Sukirti wanted to pursue law as her father was a public prosecutor.
Kandpal attended St. Mary's Convent High School, Nainital and Sophia College for Women, Mumbai.
Kandpal started her television career at the age of 19 with Jersey No. 10. She was with friends at a coffee shop, when a creative director with Cinevistaas Limited spotted her and asked her to meet him later for an audition, and was selected. Later in 2008, she replaced Shilpa Anand as Dr. Riddhima Gupta in the show Dill Mill Gayye which became a turning point in her career. In 2009, she was also seen in official music video of song Teri Yaad Mein by Kailash Kher from the album Chaandan Mein.
In early 2010, She appeared as Siddheshwari Singh in Agle Janam Mohe Bitiya Hi Kijo and also had a small cameo appearance in film Love Sex Aur Dhokha (2010). Later in 2010, she played a double role in Balaji Telefilms' supernatural romance Pyaar Kii Ye Ek Kahaani opposite Vivian Dsena. The show was inspired from The Vampire Diaries and Twilight Saga and gave her fame and recognition.
After playing lead in three shows, she took a break and made a comeback in 2012 with the role of Jazz in Rab Se Sona Ishq. She went on to play four different persons with same face (Clones) in Life OK's Hum Ne Li Hai...Shapath's special episode "Mystery Of Clones". She also co-hosted a special episode of crime based television series "Gumrah" on Channel V & Star Plus. In 2013, she played lead role of Simran in Kaisa Ye Ishq Hai..ajab sa risk hai. She had played a Non resident Indian (NRI) character in Rab Se Sona Ishq and she again portrayed an NRI character in Kaisa Ye Ishq Hai..ajab sa risk hai. Parts of Rab Se Sona Ishq were shot in London and Kaisa Ye Ishq Hai..ajab sa risk hai in Singapore. Besides doing many fiction shows, she has been part of many reality shows too. In 2014, she appeared as a contestant in Bigg Boss 8. In 2015, she played a journalist, Debjani Thakur in &TV's Dilli Wali Thakur Gurls which was one of the most popular shows on television in 2015. Show was inspired from Anuja Chauhan's novel Those Pricey Thakur Gurls and was shot in key locations in Delhi. In 2016, she was part of a travel-centered web series called Desi Explorers as host. In 2017, She made a comeback to fiction in season-2 of Zee TV's Kaala Teeka as Naina Yug Choudhary.
She was included in Eastern Eye's list of the top 50 sexiest Asian women in 2014, 2015 and 2016. An Indian lifestyle website for men, MensXP.com listed her among "35 Hottest Actresses In Indian Television". In 2016, MissMalini.com listed her among "28 Sexiest Hindi Television Actresses". She was ranked 20 in Television Personality 2015 poll by Sabras Radio for her show Dilli Wali Thakur Gurls. She is a regular face of annual Telly Calendar featuring popular television actresses by Marinating Films and Balaji Telefilms and has been part of its all six editions till 2017.
She was awarded with Aadhi Aabadi Women Achievers award in 2013 along with 18 other Indian women for her outstanding contribution in her field.
She represented India (as Miss India Worldwide India) in Miss India Worldwide contest 2011 held in Dubai, won the title Miss Bollywood Diva and was one of the Top ten contenders among the participants spanning over 30 countries. In 2016, She was one of the judges to Mrs. India Dubai International Beauty Pageant 2016, held in Dubai.