Mycobacterium haemophilum

Updated on Dec 09, 2024

Edit

Comment

Kingdom Bacteria Order Actinomycetales Family Mycobacteriaceae Scientific name Mycobacterium haemophilum Rank Species		Phylum Actinobacteria Suborder Corynebacterineae Genus Mycobacterium Higher classification Mycobacterium

Similar Mycobacterium, Mycobacterium malmoense, Bacteria, Mycobacterium scrofulaceum, Mycobacterium gordonae

Mycobacterium haemophilum is a species of the phylum Actinobacteria (Gram-positive bacteria with high guanine and cytosine content, one of the dominant phyla of all bacteria), belonging to the genus Mycobacterium.

Description

Short, occasionally curved, gram-positive, nonmotile and strongly acid-fast rods.

Colony characteristics

Nonpigmented and rough to smooth colonies.

Physiology

Media have to be supplemented with 0.4% haemoglobin or 60 µM hemin (factor X) or 15 mg/ml ferric ammonium citrate respectively, but not with FeCl₃ or catalase.

Slow growth on Löwenstein-Jensen media or Middlebrook 7H10 agar at 32 °C within 2–4 weeks.

Growth slower at 25 °C and 35 °C and absent at 37 °C.

Strictly intracellular growth in tissue cultures of fibroblasts.

Differential characteristics

Unique among mycobacteria in its requirement for hemin or ferric ammonium citrate for growth.

Distribution.

Pathogenesis

Infects patients with suppressed immune systems.

Clinical presentation: multiple skin nodules occurring in clusters or without definitive pattern, commonly involving the extremities. Abscesses, draining fistulas and osteomyelitis may be associated with the nodules. Paediatric patients with localised cervical lymphadenopathy.

Biosafety level 2

Type strain

First isolated in Israel from a subcutaneous granuloma from a patient with Hodgkin's disease. An environmental reservoir is presumed. Strain ATCC 29548 = CCUG 47452 = CIP 105049 = DSM 44634 = NCTC 11185.

References

Mycobacterium haemophilum Wikipedia

(Text) CC BY-SA

Contents

Description

Pathogenesis

Type strain

References