Trisha Shetty (Editor)

Mycobacterium haemophilum

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Kingdom
  
Bacteria

Order
  
Actinomycetales

Family
  
Mycobacteriaceae

Scientific name
  
Mycobacterium haemophilum

Rank
  
Species

Phylum
  
Actinobacteria

Suborder
  
Corynebacterineae

Genus
  
Mycobacterium

Higher classification
  
Mycobacterium

Mycobacterium haemophilum jcmasmorgcontent4872636F1largejpg

Similar
  
Mycobacterium, Mycobacterium malmoense, Bacteria, Mycobacterium scrofulaceum, Mycobacterium gordonae

Mycobacterium haemophilum is a species of the phylum Actinobacteria (Gram-positive bacteria with high guanine and cytosine content, one of the dominant phyla of all bacteria), belonging to the genus Mycobacterium.

Contents

Description

Short, occasionally curved, gram-positive, nonmotile and strongly acid-fast rods.

Colony characteristics

  • Nonpigmented and rough to smooth colonies.

    • Physiology

  • Media have to be supplemented with 0.4% haemoglobin or 60 µM hemin (factor X) or 15 mg/ml ferric ammonium citrate respectively, but not with FeCl3 or catalase.
  • Slow growth on Löwenstein-Jensen media or Middlebrook 7H10 agar at 32 °C within 2–4 weeks.
  • Growth slower at 25 °C and 35 °C and absent at 37 °C.
  • Strictly intracellular growth in tissue cultures of fibroblasts.

    • Differential characteristics

  • Unique among mycobacteria in its requirement for hemin or ferric ammonium citrate for growth.

    • Distribution.

    Pathogenesis

  • Infects patients with suppressed immune systems.
  • Clinical presentation: multiple skin nodules occurring in clusters or without definitive pattern, commonly involving the extremities. Abscesses, draining fistulas and osteomyelitis may be associated with the nodules. Paediatric patients with localised cervical lymphadenopathy.
  • Biosafety level 2

    • Type strain

    First isolated in Israel from a subcutaneous granuloma from a patient with Hodgkin's disease. An environmental reservoir is presumed. Strain ATCC 29548 = CCUG 47452 = CIP 105049 = DSM 44634 = NCTC 11185.

    References

    Mycobacterium haemophilum Wikipedia
    (Text) CC BY-SA