Trisha Shetty (Editor)

Invasive urothelial carcinoma

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Oncology

Invasive urothelial carcinoma

Invasive urothelial carcinoma is a type of Transitional cell carcinoma (TCC, also urothelial cell carcinoma or UCC) and is a type of cancer that develops in the urinary system: the kidney, urinary bladder, and accessory organs. It is the most common type of bladder cancer and cancer of the ureter, urethra, and urachus.

Contents

Invasive urothelial carcinoma originates from tissue lining the inner surface of these hollow organs - transitional epithelium. It can extend from the kidney collecting system to the bladder.

Generally speaking, Invasive urotherlial carcinoma is a cancer of the urothelium that develops from epithelial cells lining the lumens of urinary system organs. The term Carcinoma (from the Greek karkinos, or "crab", and -oma, "growth") is a type of cancer A carcinoma is a cancer that begins in a tissue that lines the inner or outer surfaces of the body, and that generally arises from cells originating in the endodermal or ectodermal germ layer during embryogenesis. Is a form of cancer of one type of Urothelial lesion and a form of Papillary urothelial lesions. Urothelium (or uroepithelium) is an example of "transitional epithelium". It is the type of epithelium that lines much of the urinary tract including the renal pelvis, the ureters, the bladder, and parts of the urethra.

Symptoms

Symptoms vary between individuals and can be dependent upon the stage of growth of the carcinoma. Presence of the carcinoma can lead to be asymptomatic blood in the urine (hematuria) Hematuria can be visible or detected microscopically. Visible hematuria is when urine appears red or brown and can be seen with the naked eye. Other symptoms are not specific. Other inflammatory conditions that affect the bladder and kidney can create similar symptoms. Early detection facilitates curing the disease. Other symptoms can involve:

  • pain or burning on urination
  • the sensation of not being able to completely empty the bladder
  • the sensation of needing to urinate more often or more frequently than normal
  • These symptoms are general and also indicate less serious problems.

    Prognosis

    Prognosis is highly variable and dependent upon a multitude of factors. Reoccurrence does occur.

    Treatment

    Treatment is determined on a case-by-case basis.

    References

    Invasive urothelial carcinoma Wikipedia