Chromone

Updated on Nov 20, 2024

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Chromone 3d molecule structure c9h6o2 1 4 benzopyrone

Chromone (or 1,4-benzopyrone) is a derivative of benzopyran with a substituted keto group on the pyran ring. It is an isomer of coumarin.

Derivatives of chromone are collectively known as chromones. Most, though not all, chromones are also phenylpropanoids.

6,7-dimethoxy-2,3-dihydrochromone has been isolated from Sarcolobus globosus.

Eucryphin, a chromone rhamnoside, can be isolated from the bark of Eucryphia cordifolia.

Cromolyn (disodium cromoglicate) was found to inhibit antigen challenge as well as stress induced symptoms. Cromoglicate is used as a mast cell stabilizer in allergic rhinitis, asthma and allergic conjunctivitis.

Nedocromil sodium was found to have a somewhat longer half-life than cromolyn; however, production was discontinued in the US in 2008.

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