Trisha Shetty (Editor)

Mast cell stabilizer

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Mast cell stabilizer

4 mast cell stabilizers


Mast cell stabilizers are cromone medications used to prevent or control certain allergic disorders. They block a calcium channel essential for mast cell degranulation, stabilizing the cell and thereby preventing the release of histamine and related mediators. One suspected pharmacodynamic mechanism is the blocking of IgE-regulated calcium channels. Without intracellular calcium, the histamine vesicles cannot fuse to the cell membrane and degranulate.

Contents

As inhalers they are used to treat asthma, as nasal sprays to treat hay fever (allergic rhinitis) and as eye drops for allergic conjunctivitis. Finally in oral form they are used to treat the rare condition of mastocytosis.

Dr mona pharmacology respiration mast cell stabilizers ttt of the cough


Examples

Mast cell stabilizer medications include:

  • β2-adrenergic agonists
  • Cromoglicic acid
  • Ketotifen
  • Methylxanthines
  • Olopatadine
  • Omalizumab
  • Pemirolast
  • Quercetin
  • Nedocromil
  • References

    Mast cell stabilizer Wikipedia


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