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Acremoniumspecies are usually slow-growing and are initially compact and moist. Their hyphae are fine and hyaline, and produce mostly simple phialides. Their conidia are usually one-celled (i.e. ameroconidia), hyaline or pigmented, globose to cylindrical, and mostly aggregated in slimy heads at the apex of each phialide.
Clinical significance
The genus Acremonium contains about 100 species, of which most are saprophytic, being isolated from dead plant material and soil. Many species are recognized as opportunistic pathogens of man and animals, causing eumycetoma, onychomycosis, and hyalohyphomycosis. Infections of humans by fungi of this genus are rare, but clinical manifestations of hyalohyphomycosis caused by Acremonium may include arthritis, osteomyelitis, peritonitis, endocarditis, pneumonia, cerebritis, and subcutaneous infection.
The cephalosporins, a class of β-lactam antibiotics, were derived from Acremonium (which used to be known as "Cephalosporium").
