Supriya Ghosh (Editor)

1 Propanol

Updated on
Share on FacebookTweet on TwitterShare on LinkedInShare on Reddit
3DMet  B00883
Formula  C3H8O
Molar mass  60.09502 g/mol
IUPAC ID  Propan-1-ol
Classification  Alcohol
Appearance  Colorless liquid
Boiling point  97 °C
Density  803 kg/m³
Melting point  -126 °C
1-Propanol structuresearchmerckchemicalscomgetImageMDAC

Related compounds  Butane Propanamine Ethanol Butanol

Organic conversion 2 propanol to 1 propanol secondary alcohol to primary alcohol

1-Propanol, is a primary alcohol with the formula CH3CH2CH2OH (sometimes represented as PrOH or n-PrOH). This colorless liquid is also known as propan-1-ol, 1-propyl alcohol, n-propyl alcohol, and n-propanol. It is an isomer of isopropanol (2-propanol, isopropyl alcohol). It is formed naturally in small amounts during many fermentation processes and used as a solvent in the pharmaceutical industry mainly for resins and cellulose esters.


1-Propanol 1Propanol Wikipedia

Espectro de infrarrojo de alcoholes 1 propanol

Chemical properties

1-Propanol 1propanol Viquipdia l39enciclopdia lliure

1-Propanol shows the normal reactions of a primary alcohol. Thus it can be converted to alkyl halides; for example red phosphorus and iodine produce n-propyl iodide in 80% yield, while PCl3 with catalytic ZnCl2 gives 1-chloropropane. Reaction with acetic acid in the presence of an H2SO4 catalyst under Fischer esterification conditions gives propyl acetate, while refluxing propanol overnight with formic acid alone can produce propyl formate in 65% yield. Oxidation of 1-propanol with Na2Cr2O7 and H2SO4 gives only a 36% yield of propionaldehyde, and therefore for this type of reaction higher yielding methods using PCC or the Swern oxidation are recommended. Oxidation with chromic acid yields propionic acid.


1-Propanol What is the structural formula of 1propanol Quora

1-Propanol is manufactured by catalytic hydrogenation of propionaldehyde. The propionaldehyde is itself produced via the oxo process, by hydroformylation of ethylene using carbon monoxide and hydrogen in the presence of a catalyst such as cobalt octacarbonyl or a rhodium complex.

H2C=CH2 + CO + H2 → CH3CH2CH=O CH3CH2CH=O + H2 → CH3CH2CH2OH

A traditional laboratory preparation of 1-propanol involves treating n-propyl iodide with moist Ag2O.

1-Propanol 1Propanol Wikipedia

1-Propanol was discovered in 1853 by Chancel, who obtained it by fractional distillation of fusel oil. Indeed, 1-propanol is a major constituent of fusel oil, a by-product formed from certain amino acids when potatoes or grains are fermented to produce ethanol. This process is no longer a significant source of 1-propanol.


1-Propanol 1Propanol anhydrous 997 CH3CH2CH2OH SigmaAldrich

1-Propanol is thought to be similar to ethanol in its effects on human body, but 2-4 times more potent. Oral LD50 in rats is 1870 mg/kg (compared to 7060 mg/kg for ethanol). It is metabolized into propionic acid. Effects include alcoholic intoxication and high anion gap metabolic acidosis. As of 2011, only one case of lethal 1-propanol poisoning was reported.


1-Propanol 2Phenyl1propanol 97 SigmaAldrich

Although this method is rare, it does exist. Propanol might be much more convenient than ethanol for inhalation because of its potency with nebulizers.

Propanol as fuel

1-propanol has high octane numbers and it is suitable to engine fuel usage. However, production of propanol has been too expensive to be a common fuel. The research octane number (RON) of propanol is 118 and anti-knock index (AKI) is 108.


1-Propanol Wikipedia