Species Human Entrez 9100 | Human Mouse Ensembl ENSG00000103194 | |
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Aliases USP10, UBPO, ubiquitin specific peptidase 10 External IDs MGI: 894652 HomoloGene: 31294 GeneCards: USP10 | ||
Ubiquitin specific peptidase 10, also known as USP10, is an enzyme which in humans is encoded by the USP10 gene.
Contents
Function
Ubiquitin is a highly conserved protein that is covalently linked to other proteins to regulate their function and degradation. This gene encodes a member of the ubiquitin-specific protease family of cysteine proteases. The enzyme specifically cleaves ubiquitin from ubiquitin-conjugated protein substrates. The protein is found in the nucleus and cytoplasm. It functions as a co-factor of the DNA-bound androgen receptor complex, and is inhibited by a protein in the Ras-GTPase pathway. The human genome contains several pseudogenes similar to this gene.
Interactions
USP10 has been shown to interact with G3BP1.
References
USP10 Wikipedia(Text) CC BY-SA