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Tromantadine

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Trade names
  
Viru-Merz

CAS Number
  
53783-83-8

CAS ID
  
53783-83-8

Routes of administration
  
Topical (gel)

Molar mass
  
280.406 g/mol

Tromantadine

AHFS/Drugs.com
  
International Drug Names

ATC code
  
D06BB02 (WHO) J05AC03 (WHO)

Legal status
  
US: Not FDA-approved OTC (RU)

Tromantadine is an antiviral medicine used to treat herpes simplex virus. It is available in a topical gel under trade names Viru-Merz and Viru-Merz Serol. Its performance is similar to aciclovir.

Contents

Like rimantadine, amantadine, and adapromine, tromantadine is a derivative of adamantane.

What does tromantadine mean


Mechanism

Tromantadine inhibits the early and late events in the virus replication cycle. It changes the glycoproteins of the host cells, therefore impeding the absorption of the virus. It inhibits penetration of the virus. It also prevents uncoating of the virions.

References

Tromantadine Wikipedia


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