Born in Toronto, Ontario to Jamaican parents Yvonne Brown and Steve Hunter, Cameron attended St. Joseph's Secondary School in Mississauga, Ontario where she played basketball for three years and soccer for one year.
A NSCAA second team All-American and two-time first team All-Big Ten selection, Cameron left Ohio State as the Buckeyes' all-time leading goal scorer with 40 and earned 96 career points, also the most in the school's history. During her senior year in 2012, she led the Buckeyes with 21 goals, breaking the previous school record of 13. Cameron's nine game-winning goals were the most in the country and her 19 career game-winners tied for fourth-most in Big Ten history.
In February 2013, Tiffany Cameron signed with the Seattle Reign FC for the inaugural season of the NWSL.
On June 19, 2013 Seattle Reign FC released Tiffany Cameron and Lyndsey Patterson shortly after signing with Megan Rapinoe, Stephanie Cox and Kennya Cordner due NWSL rules. On June 26, 2013, Cameron signed with FC Kansas City.
On February 2, 2014, Cameron signed for German team TSG 1899 Hoffenheim .
On March 9, 2015, Cameron signed with Apollon Limassol to participate in the UEFA Champions League group stage matches in August. She made three Champions League appearances and scored three goals. Her team needed either a win or tie in their last match in order to move on to the round of 32 and failed to do so.
On October 1, 2015, Cameron signed with F.C. Ramat HaSharon in the Israeli top-division Israeli First League. She won the golden boot, scoring 38 goals in 24 matches and helped her team capture their first ever League Championship.
On June 7, 2016, Cameron signed with Borussia Mönchengladbach who was promoted to the German Bundesliga for the 2016/2017 season.
Cameron earned her first three caps with the Canada women's national soccer team in January 2013 during the Four Nations Tournament in China. She previously represented Canada as a member of the Canada U-17 women's national team. She played in four matches at the FIFA U-17 Women's World Cup, held in Auckland, New Zealand where she started all four matches and helped the team to the quarterfinal round. She also played in the CONCACAF U17 championships in 2008 in Trinidad and Tobago and led the bronze-medal winning Canadian team in scoring. Tiffany also won a bronze medal with Ontario at the 2007 U16 Girls National All-Star Championship, an event where she won the Top Scorer award.