Group Group V ((−)ssRNA) Family Rhabdoviridae | Order Mononegavirales Rank Genus | |
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Tibrovirus is a genus of viruses n the family Rhabdoviridae, order Mononegavirales. Cattle and water buffalo serve as natural hosts.
Contents
Taxonomy
Table legend: "*" denotes type species.
Structure
Tibrovirions are enveloped, with bullet shaped geometries. Tibrovirus genomes are linear, around 13.2 kb in length. The genome codes for 8 proteins.
Life Cycle
Viral replication is cytoplasmic. Entry into the host cell is achieved by attachment of the viral G glycoproteins to host receptors, which mediates clathrin-mediated endocytosis. Replication follows the negative stranded RNA virus replication model. Negative stranded RNA virus transcription, using polymerase stuttering is the method of transcription. The virus exits the host cell by budding, and tubule-guided viral movement. Cattle and water buffalo serve as the natural host.