Rahul Sharma (Editor)

Thrombophlebitis

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Specialty
  
cardiology

ICD-9-CM
  
451

MeSH
  
D013924

ICD-10
  
I80, I82.1

MedlinePlus
  
001108

Thrombophlebitis

Thrombophlebitis is phlebitis or vein inflammation related to a thrombus, which is a blood clot. When it occurs repeatedly in different locations, it is known as thrombophlebitis migrans, (migrating thrombophlebitis) indicated by the Trousseau sign of malignancy.

Contents

Signs and symptoms

The following symptoms/signs are often, but not always, associated with thrombophlebitis: Although,one should note that thrombophlebitis is not restricted to the veins of the lower limbs (leg).

Causes

Thrombophlebitis causes include disorders related to increased tendency for blood clotting and reduced speed of blood in the veins such as prolonged immobility; prolonged traveling (sitting) may promote a blood clot leading to thrombophlebitis but this occurs relatively less. High estrogen states such as pregnancy, estrogen replacement therapy, or oral contraceptives are associated with an increased risk of thrombophlebitis. Specific disorders associated with thrombophlebitis include superficial thrombophlebitis which affects veins near the skin surface, deep venous thrombosis which affects deeper veins, and pulmonary embolism. Those with familial clotting disorders such as protein S deficiency, protein C deficiency, or factor V Leiden are also at increased risk of thrombophlebitis. Thrombophlebitis can be found in people with vasculitis including Behçet's disease. Thrombophlebitis migrans can be a sign of malignancies such as pancreatic carcinoma.

Complications

In terms of complications, one of the most serious occurs when the superficial blood clot is associated with a deeper venous thrombosis; this can then dislodge, traveling through the heart and occluding the dense capillary network of the lungs This is a pulmonary embolism which can be life-threatening to the affected individual.

Diagnosis

The diagnosis for thrombophlebitis is primarily based on the appearance of the affected area. Frequent checks of the pulse, blood pressure, and temperature may be required. If the cause is not readily identifiable, tests may be performed to determine the cause, including the following:

  • Doppler ultrasound
  • Extremity arteriography
  • Blood coagulation studies (Blood clotting tests)
  • Prevention

    Prevention consists of walking, drinking fluids and if currently hospitalized, changing of IV lines. Walking is especially suggested after a long period seated, particularly when one travels.

    Treatment

    In terms of treatment for this condition the individual may be advised to do the following: raise the affected area to decrease swelling, and relieve pressure off of the affected area so it will encounter less pain. In certain circumstances drainage of the clot might be an option. In general, treatment may include the following:

    Epidemiology

    Thrombophlebitis occurs almost equally between women and men, though males do have a slightly higher possibility. The average age of developing thrombophlebitis, based on analyzed incidents, is 54 for men and 58 for women.

    References

    Thrombophlebitis Wikipedia