Species Human Entrez 51497 | Human Mouse Ensembl ENSG00000101158 | |
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Aliases NELFCD, NELF-C, NELF-D, TH1, TH1L, HSPC130, negative elongation factor complex member C/D External IDs MGI: 1926424 HomoloGene: 9496 GeneCards: NELFCD | ||
Negative elongation factor C/D is a protein that in humans is encoded by the TH1L gene.
Contents
Function
The NELF complex of proteins interacts with the DSIF protein complex to repress transcriptional elongation by RNA polymerase II. The protein encoded by this gene is an essential part of the NELF complex. Alternative translation initiation site usage results in the formation of two isoforms with different N-termini.
Interactions
TH1L has been shown to interact with:
References
TH1L Wikipedia(Text) CC BY-SA