Strictosidine beta glucosidase

3alpha(S)-strictosidine beta-glucosidase (EC 3.2.1.105) is an enzyme with systematic name strictosidine beta-D-glucohydrolase. This enzyme catalyses the following chemical reaction

Thus, the two substrates of this enzyme are strictosidine and H₂O, whereas its two products are D-glucose and strictosidine aglycone.

This enzyme belongs to the family of hydrolases, specifically those glycosidases that hydrolyse O- and S-glycosyl compounds. This enzyme participates in indole and ipecac alkaloid biosynthesis.

Strictosidine is a precursor of indole alkaloids.