Pubchem 161336 | ChemSpider ID 141721 | |
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Strictosidine is a terpene indole alkaloid formed by the condensation of tryptamine with secologanin by the enzyme strictosidine synthase. Strictosidine is the base molecule for numerous pharmaceutically valuable metabolites including quinine, camptothecin, ajmalicine, serpentine, vinblastine and vincristine.
Distribution
Strictosidine is found in the following plant families.
Recent efforts in metabolic engineering have permitted the synthesis of strictosidine by yeast (Saccharomyces cerevisiae). This was accomplished by adding 21 genes and 3 gene deletions.
References
Strictosidine Wikipedia(Text) CC BY-SA