Special routes of U.S. Route 41

Fort Myers business loop

U.S. Route 41 Business is a former segment of U.S. Route 41 in Downtown Fort Myers and North Fort Myers, Florida. North of State Road 80, it carries the hidden designation State Road 739.

The road begins at the interchange of US 41 and SR 82-867, historically known as the Five Points Interchange. The road briefly overlaps SR 80 along Main and Monroe Streets, where it becomes discontinuous (it once continued east along with SR 80 though downtown along the then-one-way Second and Bay Streets but those streets were turned over to city control in 2006).

Business US 41 resumes along SR 739 at SR 80, where it runs along Park Avenue (northbound) and Fowler Street (southbound) until they reach the Edison Bridge where the two streets merge. After crossing over the Caloosahatchee River BUS 41 enters North Fort Myers where it briefly becomes a six-lane undivided highway only for the divider to return north of Cabanna Avenue. The road heads north, intersecting with State Road 78. Between State Road 78 and Powell Drive, the road becomes a four-lane divided highway for the remainder of the route. The road finally ends at a former wye at US 41.

Venice business loop

U.S. Route 41 Business is a former segment of U.S. Route 41 and an existing segment of the Tamiami Trail in Venice, Florida that begins near Shamrock Boulevard in Venice Gardens and terminates at Venetia Bay Boulevard in the Eastgate section of Venice. The existing US 41 in Venice runs along the Venice Bypass (hidden SR 45A).

The entire route is in Sarasota County.

Bradenton business loop

U.S. Route 41 Business is an alternate route and former segment of U.S. Route 41 in Bradenton, Florida that begins at State Road 684 (Cortez Boulevard West) where it runs along 14th Street until it makes a sharp right turn onto 8th Avenue West and then makes another sharp left onto 9th Street West before intersecting with State Road 64 on eastbound 6th Avenue West and westbound Manatee Avenue West. The road continues north as it passes by the South Florida Museum before crossing the Green Bridge and moving onto 8th Street in Palmetto where it intersects 10th Street West, which leads to State Road 43 where the northern concurrency of U.S. Route 41 and U.S. Route 301. As 8th Street West passes by 21st Avenue West, it becomes Valencia Drive and curves to the northeast before terminating at an interchange with US 41 just south of the interchange between US 41 and US 19 in Memphis.

The entire route is in Manatee County.

Tampa business loop

U.S. Route 41 Business is an alternate route to U.S. Route 41 in Tampa, Florida that begins on the Nebraska Avenue-Florida Avenue apex in Lutz and continues south on Florida Avenue. Just south of Hillsborough Avenue (U.S. Route 92), Florida Avenue becomes a one-way street and the south-bound portion splits off into Tampa Street until it reaches its southern terminus in Downtown Tampa at US 41 and State Road 676.

U.S. Route 541 was created in 1931 as a western alternate to US 41 between Palmetto and Tampa; US 41 then followed the present US 301 between those points. In 1938, US 41 was moved from Tampa north to Lutz, and the old route became an extension of US 541. US 541 was eliminated in 1951; the route north from Tampa became US 41 Business, while south from Tampa it became US 41, with old US 41 becoming an extension of US 301.

The entire route is in Hillsborough County.

Valdosta business loop

U.S. Route 41 in Valdosta has been rerouted to run on Inner Perimeter Road from its southern intersection with S. Patterson St. to its northern terminus with N. Valdosta St. U.S. Route 41 Business runs concurrently with Georgia State Route 7 Business from the intersection of Inner Perimeter Road and S. Patterson St. (which is just south of the Valdosta city limits) north along S. Patterson St. over the James Beck Overpass onto N. Ashley St. continuing north along N. Ashley St. where it rejoins U.S. Route 41 at the intersection of N. Valdosta St. and Innter Perimeter Rd.

Macon business loop

U.S. Route 41 Business begins at the northern terminus of the US 41-129 overlap. Along the way, US 80 joins the overlap. When US 129 intersects Walnut Street, BUS US 41 turns left and runs concurrent with Georgia Route 19 until it terminates at US 41 and Georgia Route 247.

Griffin business loop

U.S. Route 41 Business (US 41 Business) in Griffin, Georgia is co-signed with Bus US 19. It begins at the intersection of US 19/41 and Georgia State Route 155, and follows GA 155 north around Griffin-Spalding County Airport. Then it turns west at Georgia State Route 16 until it curves onto Georgia State Route 92 until finally ending at a wye interchange with US 19/41.

Ringgold truck route

U.S. Route 41 Truck is a short truck detour around a low railroad bridge in Ringgold, Georgia, which is also overlapped by U.S. Route 76 Truck, as well as Georgia State Route 151 and Georgia Route 151 Spur.

Monteagle, TN-Hopkinsville, KY alternate route

U.S. Route 41 Alternate (signed U.S. Route 41A in Tennessee), as of 2005, has a northern terminus in Hopkinsville, Kentucky, 10 miles (16 km) north of the Tennessee line. It serves the city of Clarksville, Tennessee on its way to Nashville, where it briefly runs concurrently with US 41. It then separates again to serve Shelbyville, Winchester, and Tullahoma before rejoining the main route atop Monteagle Mountain. US 41A runs west of US 41 for its entire length, aside from one mile in downtown Nashville, where they are concurrent. US-41A is also concurrent with U.S. Route 31A from Nashville to Triune, Tennessee, for a distance of approximately 25 miles (40 km).

Clarksville alternate route bypass

U.S. Route 41A Bypass (US 41A Byp.) is a bypass of the city of Clarksville, Tennessee on its south side. It first splits off from the US 41A mainline at 2nd Street and Kraft, following Riverside Drive south along the Cumberland River, and then traveling concurrently with Tennessee State Route 76 past Tennessee State Route 13 and Tennessee State Route 48 where it begins bypass designation. The bypass travels to the east approximately 5 miles (8.0 km) along the edge of the Cumberland. Most of the road is a two-lane highway, occasionally widening to three lanes to accommodate truck traffic on hills. There is one light in the middle of the bypass, where Tennessee State Route 12 (Ashland City Highway) starts approximately 1.5 miles (2.4 km) before the bypass merges with US 41A (Madison Street) on the east side of Clarksville. From here, US 41A heads southeast to Nashville, Tennessee, where it merges with US 41.

Hopkinsville truck route

U.S. Route 41 Truck (US 41 Truck) is a bypass route designed for thru traffic, mainly trucks through Hopkinsville, Kentucky. It follows the Pennyrile Parkway from exit 7 to exit 12, and Kentucky Route 1682 west from the interchange to U.S. 41 north of Hopkinsville.

Madisonville-Henderson alternate route

Known and referred to locally as "U.S. 41-A" but signed as "Alternate U.S. 41," this route follows what was the original route of U.S. 41 between the cities of Madisonville and Henderson, Kentucky. It travels largely from east to west from its southern terminus at U.S. 41 on Madisonville's north side until reaching Kentucky Route 814 east of Providence. From that point, the road begins its turn toward the north, passing mostly through rural areas but also serving the small communities of Dixon and Poole.

Major highways intersecting the route include:

41-A's northern terminus is at "The Cloverleaf," the interchange between U.S. 60 and U.S. 41/Pennyrile Parkway on Henderson's north side.

Illinois toll route

U.S. Route 41 Toll was the original designation for the Tri-State Tollway, which opened in 1958. By 1959, the route was replaced by parts of I-94 and I-294.

Marquette business loop

Business US Highway 41 (Bus.  41) was a state trunkline highway that served as a business loop off US 41 in Michigan through the city of Marquette along Washington and Front streets after the construction of an expressway bypass of downtown. Jurisdiction over the two streets was transferred to the city as part of a route swap that resulted in the decommissioning of the trunkline. It was also previously co-designated Bus. M-28, mirroring the Bus. US 41/Bus. M-28 designations along Bus. M-28 in Ishpeming and Negaunee.

Ishpeming-Negaunee business loop

Business U.S. Highway 41 (Bus. US 41) served Ishpeming and Negaunee is the only one of the three former business loops in Michigan that is still a state-maintained highway, although it is no longer designated Bus. US 41. US 41/M-28 was relocated to bypass the two cities' downtowns in 1937. The highway through downtown Ishpeming and Negaunee was redesignated US 41A/M-28A at the time The Michigan State Highway Department later redesignated it Alt. US 41/Alt. M-28. Eventually it carried the Bus. US 41/Bus. M-28 designation before being designated just Bus. M-28 in 1958.

Baraga business loop

Business U.S. Highway 41 (Bus. US 41) existed in Baraga in the early 1940s. As shown on the maps of the time, US 41 was relocated in Baraga between the publication of the December 1, 1939, and the April 15, 1940, MSHD maps. A business loop followed the old routing through downtown. The last map that shows the loop was published on July 1, 1941. Bus. US 41 is shown under local control on the June 15, 1942, map.