| 1923 – present|
| US 21 / US 176 / US 321 in Cayce|
US 378 in West Columbia
Lexington County, South Carolina
South Carolina Highway 2 (SC 2) is a state highway in the U.S. state of South Carolina that runs 3.9 miles (6.3 km) between two portions of U.S. Highway 21/U.S. Highway 176/U.S. Highway 321 (US 21/US 176/US 321) in Lexington County. The southern 2.4 miles (3.9 km) of the highway are known as Frink Street while the northern 1.5 miles (2.4 km) of the highway are known as State Street.
South Carolina Highway 2 Wikipedia
SC 2 is a 3.9-mile (6.3 km), two-lane road just southwest of Columbia, serving as a business route for Cayce. It begins at the US 21/US 176/US 321 concurrency heading northeast. It then takes a turn to the north and runs parallel to the Congaree River to its west. Shortly after passing US 1, the highway ends at US 378 in West Columbia. The highway runs by an elementary school, Brookland-Cayce High School, two shopping centers, and a park.
SC 2 is one of the original state highways. The original route went from the Georgia state line north of Mountain Rest heading east towards Greenville before turning southeast and ending in Charleston, spanning over 250 miles (400 km). It was considered the state's "Main Street" in the 1920s and 1930s. The road began construction in 1923 and ended 11 years later in 1932. The road was re-designated as US 76, US 176 and US 178 in the 1940s and has been reduced to just under four miles (6.4 km).
The entire highway is in Lexington County.