Species Human Entrez 6767 | Human Mouse Ensembl ENSG00000100380 | |
Aliases ST13, AAG2, FAM10A1, FAM10A4, HIP, HOP, HSPABP, HSPABP1, P48, PRO0786, SNC6, suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) External IDs MGI: 1917606 HomoloGene: 2921 GeneCards: ST13 | ||
Hsc70-interacting protein also known as suppression of tumorigenicity 13 (ST13) is a protein that in humans is encoded by the ST13 gene.
Contents
St13 volume tony
Function
The protein encoded by this gene is an adaptor protein that mediates the association of the heat shock proteins HSP70 and HSP90. This protein has been shown to be involved in the assembly process of glucocorticoid receptor, which requires the assistance of multiple molecular chaperones. The expression of this gene is reported to be downregulated in colorectal carcinoma tissue suggesting that is a candidate tumor suppressor gene.
References
ST13 Wikipedia(Text) CC BY-SA