Rosso is a surname of Italian origin, which means red. Notable people with the surname include:
Antonio De Rosso (b. 1941), head of the Orthodox Church in Italy and the Metropolitan of Ravenna and Italy
Camilla Rosso (b. 1994), British actress, sister of Rebecca Rosso and Georgina Rosso
Frank Rosso (1921-1980), American baseball player
George Rosso (1930–1994), American professional football player
Giovanni Rosso (b. 1972), Croatian professional football player
Julee Rosso (contemporary), American cook and food writer
Medardo Rosso (1858–1928), Italian sculptor
Nini Rosso (1926–1994), Italian jazz trumpeter and composer
Patrick Rosso (b. 1969), French judoka
Renzo Rosso (b. 1955), Italian clothing designer; co-founder of the Diesel clothing company
Rebecca Rosso (b. 1994), British actress, twin sister of Camilla Rosso, and younger sister of Georgina Rosso
Stefano Rosso (1948–2008), Italian songwriter and guitarist