Routes ofadministration Oral Legal status US: ℞-only PubChem CID 16132338 | ATC code none CAS Number 76168-82-6 ChemSpider 17286439 | |
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Ramoplanin (INN) is a glycolipodepsipeptide antibiotic drug derived from strain ATCC 33076 of Actinoplanes.
Contents
Mechanism
It exerts its bacteriocidal effect by inhibiting cell wall biosynthesis, acting by inhibiting the transglycosylation step of peptidoglycan synthesis.
Uses
Its development has been fast-tracked by the U.S. Food and Drug Administration as a treatment for multiple antibiotic-resistant Clostridium difficile infection of the gastrointestinal tract, although it is unstable in the bloodstream, so can be taken only orally against such infections.
References
Ramoplanin Wikipedia(Text) CC BY-SA