Harman Patil (Editor)

RBBP5

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Species
  
Human

Entrez
  
5929

Human
  
Mouse

Ensembl
  
ENSG00000117222

RBBP5

Aliases
  
RBBP5, RBQ3, SWD1, retinoblastoma binding protein 5, RB binding protein 5, histone lysine methyltransferase complex subunit

External IDs
  
MGI: 1918367 HomoloGene: 3709 GeneCards: RBBP5

Retinoblastoma-binding protein 5 is a protein that in humans is encoded by the RBBP5 gene.

Contents

Function

The protein encoded by this gene is a ubiquitously expressed nuclear protein and belongs to a highly conserved subfamily of WD-repeat proteins. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. The encoded protein interacts preferentially with the underphosphorylated retinoblastoma protein via the E1A-binding pocket B.

Interactions

RBBP5 has been shown to interact with:

  • ASCL2,
  • MLL,
  • MLL3, and
  • NCOA6.
  • References

    RBBP5 Wikipedia