Entrez 23054 | Ensembl ENSG00000198646 | |
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Aliases NCOA6, AIB3, ASC2, NRC, PRIP, RAP250, TRBP, nuclear receptor coactivator 6 External IDs HomoloGene: 40920 GeneCards: NCOA6 | ||
Function
The protein encoded by this gene is a transcriptional coactivator that can interact with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has been shown to be involved in the hormone-dependent coactivation of several receptors, including prostanoid, retinoid, vitamin D3, thyroid hormone, and steroid receptors. The encoded protein may also act as a general coactivator since it has been shown to interact with some basal transcription factors, histone acetyltransferases, and methyltransferases.
Interactions
NCOA6 has been shown to interact with:
References
NCOA6 Wikipedia(Text) CC BY-SA