The Pseudonocardiaceae are a family of bacteria in the order Actinomycetales and the only member of the suborder Pseudonocardineae.
The species within the Pseudonocardiaceae family form a distinct clade in phylogenetic trees based on concatenated protein sequences. Additionally, Nakamurella multipartite, currently part of the order Frankiales, also formed a clade with the Pseudonocardiaceae species in 100% of the bootstrap replications of the phylogenetic trees. A conserved signature indel has been identified which is found in N. multipartite and all but one of the Pseudonocardiaceae species. This one-amino-acid insertion in UMP kinase serves to both provide a molecular marker for nearly all of the Pseudonocardiaceae and suggests N. multipartite is closely related to this group. Some evidence also suggests the orders Pseudonocardiales and Corynebacteriales are closely related. Several conserved signature indels have been identified which are found in both Pseudonocardiales and Corynebacteriales, including a three-amino-acid insertion in a conserved region of UDP-galactopyranose mutase. This insertion is also present in N. multipartite and Geodermatophilus obscurus, another member of Frankiales. Additionally, five conserved signature proteins have been identified which are found only in the Pseudonocardiales and Corynebacteriales orders. Homologs of the proteins are generally found in N. multipartite and G. obscurus, providing additional evidence of these two species being closely related to the orders Pseudonocardiales and Corynebacteriales.
The phylogeny is based on 16S rRNA-based LTP release 123 by 'The All-Species Living Tree' Project.
The currently accepted taxonomy is based on the List of Prokaryotic names with Standing in Nomenclature and National Center for Biotechnology Information
Order Pseudonocardiales Labeda & Goodfellow 2015 [Pseudonocardineae Stackebrandt et al. 1997 emend. Labeda et al. 2011; "Pseudonocardiales" Labeda & Goodfellow 2012; incl. Actinopolysporineae]Family Pseudonocardiaceae Embley et al. 1989 emend. Labeda et al. 2011 [incl. Actinopolysporaceae Zhi, Li & Stackebrandt 2009]Genus "Prauseria" ♠ Zhou, Whitehead & Goodfellow 1997Genus "Saccharothrixopsis" ♠ Wang, Qian & Liu 1999Genus Actinoalloteichus Tamura et al. 2000Genus Actinocrispum Hatano et al. 2016Genus Actinokineospora Hasegawa 1988 emend. Labeda et al. 2010Genus Actinomycetospora Jiang et al. 2008 emend. Zhang et al. 2014Genus Actinophytocola Indananda et al. 2010 emend. Sun et al. 2014Genus Actinorectispora Quadri et al. 2015Genus Actinosynnema Hasegawa, Lechevalier & Lechevalier 1978Genus Alloactinosynnema Yuan et al. 2010 emend. Nikou et al. 2014Genus Allokutzneria Labeda & Kroppenstedt 2008Genus Amycolatopsis Lechevalier et al. 1986 emend. Tang et al. 2010Genus Crossiella Labeda 2001Genus Goodfellowiella Labeda et al. 2008 [Goodfellowia Labeda & Kroppenstedt 2006 non]Genus Herbihabitans Zhang et al. 2016bGenus Haloechinothrix Tang et al. 2010Genus Kibdelosporangium Shearer et al. 1986Genus Kutzneria Stackebrandt et al. 1994 emend. Suriyachadkun et al. 2013Genus Labedaea Lee 2012Genus Lechevalieria Labeda et al. 2001Genus Lentzea Yassin et al. 1995 emend. Labeda et al. 2001 ["Asiosporangium" Runmao et al. 1995]Genus Longimycelium Xia et al. 2013Genus Prauserella Kim and Goodfellow 1999 emend. Li et al. 2003Genus Pseudonocardia Henssen 1957 emend. Park et al. 2008 [Actinobispora Jiang et al. 1991; Amycolata Lechevalier et al. 1986; Pseudoamycolata Akimov, Evtushenko & Dobritsa 1989]Genus Saccharomonospora Nonomura and Ohara 1971Genus Saccharopolyspora Lacey and Goodfellow 1975 emend. Korn-Wendisch et al. 1989 [Faenia Kurup & Agre 1983]Genus Saccharothrix Labeda et al. 1984 emend. Labeda and Lechevalier 1989Genus Sciscionella Tian et al. 2009Genus Streptoalloteichus (ex Tomita et al. 1978) Tomita et al. 1987 emend. Tamura et al. 2008Genus Tamaricihabitans Qin et al. 2015Genus Thermobispora Wang et al. 1996Genus Thermocrispum Korn-Wendisch et al. 1995Genus Thermotunica Wu et al. 2014Genus Umezawaea Labeda & Kroppenstedt 2007Genus Yuhushiella Mao et al. 2011Notes:
♠ Strains found at the National Center for Biotechnology Information, but not listed in the List of Prokaryotic names with Standing in Nomenclature
