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Philippa Marrack

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Doctoral advisor  Alan Munro
Spouse  John Kappler
Role  Biologist
Name  Philippa Marrack

Philippa Marrack wwwnaturecomnmjournalv10n12imagesnm120412
Born  28 June 1945 (age 70) Ewell, England (1945-06-28)
Alma mater  Cambridge University University of California, San Diego
Known for  T cells, autoimmune disease
Notable awards  Louisa Gross Horwitz Prize (1995) Dickson Prize (1996)
Education  University of Cambridge, University of California, San Diego
Awards  Wolf Prize in Medicine, Louisa Gross Horwitz Prize
Similar People  John Kappler, Harald von Boehmer, Christine Petit, Carlotta Walls LaNier

Institutions  National Jewish Health

Philippa Marrack - How Crucial is Competitiveness to a Scientific Career?

Philippa "Pippa" Marrack FRS (born 28 June 1945) is an English biologist, based in the United States, best known for her research into T cell development, T cell apoptosis and survival, adjuvants, autoimmune disease, and for identifying superantigens, the mechanism behind toxic shock syndrome. She collaborates with her husband, John W. Kappler.


Philippa Marrack Philippa Marrack PhD HHMIorg

2013 cshl symposium interview dr philippa marrack


Philippa Marrack Beyond Expectation The Scientist Magazine

Marrack was born in Ewell, England on 28 June 1945. She completed both undergraduate (1967) and PhD (1970) work at New Hall, Cambridge. During her PhD, she worked at the MRC Laboratory of Molecular Biology with Alan Munro, where she began to study the differences between T cells and B cells.

Philippa Marrack Philippa Marrack PhD FRS

She later did postdoctoral work with Richard Dutton at the University of California, San Diego.

Her first faculty position was with the University of Rochester, followed by National Jewish Health, Denver, Colorado and the University of Colorado.

Significant papers

  • J.W. Kappler, M. Roehm, P. Marrack, "T cell tolerance by clonal elimination in the thymus," Cell, v.49, n.2, pp. 273–80 (1987)
  • P. Marrack and J. Kappler, "The Staphylococcal Enterotoxins and Their Relatives," Science, v.248 (4956), pp. 705–11 (1990).
  • J.W. Kappler, U. Staerz, J. White, P.C. Marrack, "Self-Tolerance Eliminates T Cells Specific for MIS-Modified Products of the Major Histocompatibility Complex," Nature, 332 (6159): pp. 35–40 (1988).
  • J. White, et al. (P.C. Marrack), "The V(beta)-specific superantigen staphylococcal enterotoxin B: Stimulation of mature T cells and clonal deletions in neonatal mice," Cell, v.56, n.1, pp. 27–35 (1989).
  • Awards

  • 1986 – Appointed Investigator, Howard Hughes Medical Institute
  • 1987 – Fellow (elected), Royal Society
  • 1989 – Elected member, National Academy of Sciences
  • 1990 – Royal Society Wellcome Foundation Prize
  • 1993 – Cancer Research Institute William B. Coley Award
  • 1993 – Paul Ehrlich and Ludwig Darmstaedter Prize
  • 1994 – Louisa Gross Horwitz Prize (Columbia University)
  • 2003 – Lifetime Achievement Award, American Association of Immunologists
  • 2004 – L'Oreal UNESCO Women in Science Award
  • 2005 – Pearl Meister Greengard Prize
  • Rabbi Shai Shackner Prize (University of Jerusalem)
  • 2015 – Wolf Prize in Medicine
  • 2015 – Inducted into the National Women's Hall of Fame
  • References

    Philippa Marrack Wikipedia

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