Rahul Sharma (Editor)

Phenylsilane

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Formula
  
C6H8Si

Molar mass
  
108.22 g/mol

Density
  
878 kg/m³

Appearance
  
Colorless liquid

Phenylsilane wwwsigmaaldrichcomcontentdamsigmaaldrichstr

Phenylsilane, also known as silylbenzene, a colorless liquid, is one of the simplest organosilanes with the formula C6H5SiH3. It is structurally related to toluene, with a silyl group replacing the methyl group. Both of these compounds have similar densities and boiling points due to these similarities. Phenylsilane is soluble in organic solvents.

Contents

Synthesis and reactions

Phenylsilane is produced in two steps from Si(OEt)4. In the first step, phenylmagnesium bromide is added to form Ph-Si(OEt)3 via a Grignard reaction. Reduction of the resulting Ph-Si(OEt)3 product with LiAlH4 affords phenylsilane.

Ph-MgBr + Si(OEt)4 → Ph-Si(OEt)3 + MgBr(OEt)4 Ph-Si(OEt)3 + 3 LiAlH4 → 4 Ph-SiH3 + 3 LiAl(OEt)4

Uses

Phenylsilane can be used to reduce tertiary phosphine oxides to the corresponding tertiary phosphine.

P(CH3)3O + PhSiH3 --> P(CH3)3 + PhSiH2OH

The use of phenylsilane proceeds with retention of configuration at the phosphine. For example, cyclic chiral tertiary phosphine oxides can be reduced to cyclic tertiary phosphines.

Phenylsilane can also be combined with cesium fluoride. In aprotic solvents, it becomes a nonnucleophilic hydride donor. Specifically, phenylsilane-caesium fluoride has been shown to reduce 4-oxazolium salts to 4-oxazolines. This reduction gives yields of 95%.

References

Phenylsilane Wikipedia


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