People of the Karoo refers to notable individuals who come (or came) from, or whose lives have included substantial engagement with, the area known as the Karoo. The Karoo is a widespread physiographic province in the western interior of South Africa, straddling much of the Northern Cape, southern Free State, Eastern Cape interior and parts of the Western Cape Provinces.
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As a distinctive, generally arid region, it has given rise to a characteristic architecture, cuisine, literature and other cultural elements, with predominantly sheep farming practices, and lifestyles that included a persistence of hunting and gathering by |xam and other San (Bushman) groups into the later nineteenth century. Karoo, as place, is often acknowledged as an influential aspect in the lives or backgrounds of those people who come from or live in the region - exemplified by Guy Butler's autobiographical Karoo Morning.