Nicola came to the village to meet her older half-sister, Bernice Blackstock (Samantha Giles) and stayed with her father, Rodney (Patrick Mower). She met and became friends with Emily Kirk (Kate McGregor). Within months, Nicola became interested in chef Carlos Diaz (Gary Turner), unaware that he was involved with Bernice. She chased him for a while before they ended up in bed after Bernice dumped him, wanting to make her marriage work. Scared she might lose Carlos, Nicola announced she was pregnant and was stunned yet elated when he proposed, which she accepted.
On her hen night, Bernice caught her drinking vodka and Nicola admitted that she had lied about being pregnant. Bernice, who was herself pregnant, was horrified and insisted she tell Carlos before the ceremony. Furious that she would lie to him like that, Carlos told Nicola about his affair with Bernice and that the baby she was carrying could be his. Disgusted, Nicola attacked Bernice with her bouquet before storming into the church to announce that the wedding was off, due to Carlos's infidelity. She also told Ashley about Bernice's affair and the fact that he might not be the father of Bernice's baby. Despite her mother's suggestion that she go home with her, Nicola stayed with Rodney and eventually forgave Bernice. She became godmother to Ashley and Bernice's daughter, Gabby Thomas (Annelise Manojlovic).
Nicola's once kind and friendly attitude altered dramatically and she severed ties with Emily, although they later made up. Nicola was bridesmaid when she married Paddy Kirk (Dominic Brunt) in October 2002. She argued frequently with postmistress, Viv Hope (Deena Payne), and local siren Chloe Atkinson (Amy Nuttall), and caused heartbreak when she seduced Robert Sugden (Karl Davies). She dumped Robert by allowing him to see her having sex with builder Syd Woolfe (Nathan Gladwell) in her living room. Nicola had a brief relationship with Syd, which ended when she discovered that he was also having an affair with Chloe, who was dating Scott Windsor (Ben Freeman) at the time.
After successfully starting a cleaning business and employing Pearl Ladderbanks (Meg Johnson), Betty Eagleton (Paula Tilbrook) and Laurel Thomas (Charlotte Bellamy), Nicola met fishmonger Simon Meredith (Dale Meeks) in November 2003 and after a bumpy start, they began dating. However, there were many obstacles, such as his ex-fiancée Tash Abbott (Sally Evans) and his mother, Lesley Meredith (Sherrie Hewson). Nicola was desperate to settle down and dreamed of the perfect marriage. After they got engaged, Lesley constantly caused trouble and even stole Kelly Windsor's (Adele Silva) credit card and eventually her debts began mounting up. This resulted in Lesley and Simon losing everything, forcing him and Nicola to postpone the wedding. Bored with Simon and their financial problems, Nicola tried repeatedly to seduce her half-brother Paul Lambert's (Matthew Bose) bisexual lover, Ivan (Daniel Brocklebank), who was mates with Simon. After failing, Nicola plied Ivan with alcohol and tried again, a moment witnessed by Lesley. Assuming that they were having an affair, Lesley told her son about Nicola's "infidelity" so Simon ended the relationship. Nicola was disgraced as she also destroyed Ivan and Paul's relationship, leading Paul and Rodney to disown her so Nicola left the village in March 2006.
Nicola returned in September 2007 with a business proposition for David Metcalfe (Matthew Wolfenden). He owned what had been Laurel and Nicola's cleaning business and she wanted it back. Nicola claimed she was a wealthy widow and restarted her cleaning empire, threatening to put David out of business. After meeting him a few times, she returned to an unenthusiastic response. Nicola pursued David, despite him dating Jasmine Thomas (Jenna-Louise Coleman). Nicola and David slept together and Jasmine caught them so she ended things with David and exposed Nicola's lie that she was a widow, as Donald was alive. He was in a coma, following a brain haemorrhage. Nicola told Rodney and Paul that she had said he was dead because unless she could prove Donald's son, Miles, was still drinking, he would inherit Donald's estate so Nicola kept Donald alive until she had the proof she needed and then she would switch the machines off. However, Jasmine got Miles back on the wagon. On 28 December, Nicola was called to the hospital and was stunned to learn that Donald was conscious. He claimed not to remember her and spent the evening with Miles. Realizing Donald could make a full recovery, Nicola planned to murder him and asked David to help her but, disgusted, he refused to get involved and sabotaged her plots and told Donald, who confronted her on some local cliffs, giving her the perfect opportunity. Shocked, she confessed and even tried to save him when it looked like he could go over the edge. He agreed not to tell the police, providing she left his house immediately and David didn't want her either.
Rodney, unaware of this, rented Mill Brook Cottage and made it clear that she'd have to pay half the rent. She asked David for a job but all he offered was scrubbing floors. She worked for him briefly but went to work for Paddy as his chauffeur after accidentally injuring him, so he was unable to drive. Nicola spent most of her time with Rodney and attempted to become respectable again. When celebrity chef Anthony Worrall Thompson visited, Nicola tried to get to know him and was soon bragging that they were going to work together but was embarrassed when Bob gave her a message from Anthony's people, asking her to stop bothering him.
In June 2008, Nicola started dog-sitting briefly. Rodney was unhappy about it but it was a way of earning money and Val Pollard's (Charlie Hardwick) daughter, Sharon Lambert (Victoria Hawkins), used her contacts to help Nicola get started as she had a friend that needed someone to look after her dog while she was abroad. David helped Nicola find some missing dogs one day and they reconciled after hearing Sharon telling a friend that she wasn't that interested in David. Nicola told Sharon and they had a fight in The Woolpack until David separated them and ended Nicola's dog-sitting business as Sharon was no longer prepared to help her get started but Nicola soon came up with another money-making scheme. Rodney had been trying to cheer Gabby up after she learnt about the baby swap involving Daniel and Arthur by telling her stories based on his fairground days. Nicola sold the stories to a publisher, claiming that her father was dead, and they were due to be published in March 2009 but Rodney found out and gave her an ultimatum - tell the truth or stop calling him Dad. She refused so he kicked her out. She moved in with Edna Birch (Shirley Stelfox), following brief stays with the Pollards and her brother, Paul and Katie Sugden (Sammy Winward).
When Nicola discovered that Ashley Thomas's (John Middleton) boss told him that they were considering closing the church in late 2008, she and David planned to buy it and make it their dream home. However, there was a problem: the church choir. Nicola planned to ruin the choir by telling Laurel and Ashley she was there to help them but making the choir so bad, they would have no chance in a competition. In November, she changed her mind after becoming closer to her family and friends because they were impressed by her attempts to help the community. She focused her efforts on saving the church by helping the choir sing "O Happy Day". David and Eric discovered what she was up to and tried to sabotage the choir. They failed and the choir won a special recognition award so David and his father, Eric Pollard (Chris Chittell), revealed Nicola's original plan so she was shunned by everyone. Nicola worked hard to convince people that she was truly reformed and wanted them to succeed. She made headway on 15 December, just after the competition, when she was allowed to collect Gabby from playgroup. On 19 December, Edna asked Nicola to move out so her sister, Lily (Anne Charleston), could move in. Now homeless and alone, she moved into the church so Laurel took pity on her, asking her to stay with her and Ashley. On 25 December, after the Christmas Service, Nicola started a sit-in protest in the church to stop its closure with the choir in tow. They convinced Eric and David not to buy the church but the church was still for sale. The church was purchased by newcomers Mark Wylde (Maxwell Caulfield) and Natasha Wylde (Amanda Donohoe) who also bought Home Farm Estates. The villagers convinced the Wyldes to let them have the church and Nicola applied for the position of estate manager at Home Farm and got it when she impressed Natasha, rather than keep Rodney on, as she admired her determination. Nicola often struggled to stay within her boundaries as she was expected to be the Wyldes' personal assistant too.
In February 2009, Nicola and Jimmy King (Nick Miles) drowned their sorrows in The Woolpack and carried on drinking in an Emmerdale Haulage van. They spent the night together and woke up to discover themselves en route to Hull. Nicola was horrified but Jimmy was more amused and they got a cab back to Emmerdale. Nicola asked Jimmy to hide when they saw David but he saw Jimmy and laughed at them. Nicola was embarrassed and rebuffed Jimmy's attempts at a relationship. After several weeks, Nicola asked Jimmy to accompany her when Mark and Natasha invited her to dinner. She thought their motive was much more personal but Jimmy was unhappy about returning to Home Farm and drank more than he should. Nicola, humiliated by the Wyldes, also got drunk and they spent the night together again. Nicola pushed Jimmy away but was intrigued when Rodney told her Jimmy may not be as broke as she thought. Thinking he had money hidden away in Switzerland, Nicola charmed her way back into his bed and convinced him that she cared about him, when he said he was going there. Jimmy guessed her true intentions and humiliated her by wining and dining her, then telling her that they were going to Switzerland in the haulage truck and telling everyone that she was a "gold-digger". Nicola was furious. In spite of the couple's rocky start, they were still attracted to each other so in order to make more room in the vicarage, Ashley's father, Sandy (Freddie Jones), and Laurel's father, Doug, wrote a love letter from "Jimmy". Nicola was moved by the romantic prose and visited him. After a passionate night, she told Jimmy she would move in with him, as this was what he had asked her. Jimmy was stunned but kept quiet as he didn't want to lose her but they argued constantly and after one row too many, Jimmy dumped her. Carl and Lexi insisted she move out so Laurel asked her to move back in with her.
Nicola told Laurel on 8 May 2009 that she thought she was pregnant. Laurel persuaded her to do a test and a few days later, Nicola learned that she was 17 weeks pregnant. Shocked, she insisted the doctor was wrong as she was sure that she and Jimmy had always been careful, except the night they spent in the van. She considered an abortion and even booked an appointment but cancelled it after discussing it with Laurel and Rodney. Laurel also talked her out of putting the baby up for adoption, assisted by Lexi. Nicola returned to Mill Cottage with Jimmy and started looking forward to the arrival of their baby. Lexi King (Sally Oliver) was surprised that Nicola hadn't started thinking about the nursery so when her pregnancy was confirmed, they went shopping for nursery furniture. Unfortunately Lexi's pregnancy was ectopic and the tube burst, so it had to be removed. Nicola supported Lexi but tried not to be there too much, fearing that her now obvious pregnancy was making Lexi feel worse. She also backed her up when Carl King (Tom Lister) made excuses about not being able to go to IVF clinic with Lexi. Jimmy later told her that Carl had admitted that he didn't want any more children and was only going ahead with the IVF to please Lexi but Nicola warned Carl that he had to tell Lexi the truth or she would. He did on 3 August and Lexi told him to leave, which he did. Still angry, Lexi blamed Nicola when she tried to comfort her and pushed her away, causing her to fall down the stairs after a vicious row, leaving her unconscious. Horrified by what she'd done, Lexi called an ambulance and Nicola was rushed to hospital. Luckily, she was discharged the same day but went into labour a few days later, while locked in the farm shop. Luckily Rodney and Cain got her to the hospital before she gave birth to a baby girl, with Jimmy at her side. The little girl was put in an incubator and rushed away for further treatment, but Nicola and Jimmy are reassured by the doctor that their little girl is going to be fine, naming her Angelica. When baby Angelica was taken away for further tests, Nicola took a shower and the nurse gave Angelica to Lexi, who took her up on to the roof, just to show her the view. Unfortunately Nicola and Jimmy misunderstood what Lexi was doing and panicked. Lexi returned the baby to Jimmy and Nicola before having a rooftop showdown with Carl about their relationship.
Nicola soon returns to work, putting Angelica into play group, and after seeing Viv and Bob Hope's (Tony Audenshaw) daughter, Cathy (Gabrielle Dowling), biting another child, Nicola bit her so Cathy would know what it felt like. However, Viv called the police and they pressed charges. A custodial sentence was possible but Viv wrote a letter to the court, asking them to show leniency as she hadn't thought the case would go to court so Nicola was sentenced to probation.
In July 2010, Nicola and Jimmy considered buying The Woolpack, assisted by Jimmy's half-sister, Scarlett Nicholls (Kelsey-Beth Crossley), but pull out in September as Nicola fears she cannot cope with being landlady and a new mother.
in February 2011, Nicola discovers Jimmy has been involved in an accident and is receiving treatment in hospital. However, on arrival, she is shocked to learn he has lost all memory and has no idea who she or Angelica are. Jimmy is persuaded by Kelly that she and him were having an affair before his accident and that he was ready to leave Nicola. Jimmy and Nicola split as Jimmy takes Kelly's side of the story and the pair get together, with the son Kelly tells him is his. Jimmy's memory begins to return and he sees Kelly's true colours. Despite this, Nicola is hurt that Jimmy has slept with Kelly, and refuses to get back with him. The pair prepare for a divorce but after an argument in September 2011, the pair end up in a passionate kiss.
In 2013 Nicola wants to send Angelica to a posh school but when Jimmy tells her they cannot afford it she is loaned the money from Bernice's boyfriend Steve Harland who is only too happy to give her it as he is attracted to her. A few weeks after Nicola and Steve are sitting in Steve's having wine and they kiss. Nicola quickly backs away and attempt's to leave but Steve stops her telling her that he enjoys spending time with her and what Jimmy and Bernice don't know won't hurt them. The next day Steve tells Nicola he has booked a hotel room for them and she considers going but after playing with Jimmy and Angelica she relies that she could never cheat on Jimmy but when she tells Steve this he tells her that if she doesn't sleep with him then she will have to give him his money back and if she tells anyone he will tell everyone that they have been having an affair and that she stole 10 grand of him. When she arrives at the hotel she tells him the best offer he is going to get is 1 night with her then they are quits, after she agrees he kisses her and try's to undress her just as Bernice walks in and reveals that Nicola told her everything but Steve tells them both that Bernice has been using him and that she isn't as special as she thinks and before he leaves the hotel he warns Nicola that "she isn't coming out of this squeaky clean" and she relies she will have to tell Jimmy everything before Steve does. The next day Nicola tells Jimmy that she has been borrowing money from Steve and that he has been trying to blackmail her into sleeping with him and Jimmy is furious, he goes outside and finds Steve and smashes his van up, after Steve tells Ashley Thomas, Rodney Blackstock and Diane Sugden what he thinks of them Jimmy gives Steve a check for 10 grand but after Steve makes a nasty comment about Nicola Jimmy punches him and tells him if he ever sees his face again he will rip it off Steve then leaves the village. Nicola and Jimmy's marriage becomes very strained over the next couple of weeks until Nicola is one of the people taken her brother in laws escaped killer Cameron Murray when she is free her and Jimmy reminisce.
Jimmy and Nicola are still together even after she miscarries their baby and in 2015 she goes and works at the Atlantis hotel in Dubai when Jimmy and Angel were still in Yorkshire. She returned in November 2015 it was revealed she was deported from Dubai, she is shocked to see Jimmy has sold their house so breaks into it.
In June 2016 Nicola gets caught in a fire started by Rakesh Kotecha (Pasha Bocarie). She is pulled out by Ronnie Hale (John McArdle) and Dan Spencer (Liam Fox) and taken to hospital. She discharges herself the next day and Jimmy takes her home. She later collapses and Jimmy calls an ambulance. She is told that she is partially paralysed and that she might never walk again.
Nicola Blackstock was first introduced by series producer Kieran Roberts, who cast Nicola Wheeler in 2001. She arrived after getting in touch with her father Rodney (Patrick Mower). He had come to Emmerdale to get to know his older daughter, Bernice Thomas (Samantha Giles). In January 2006, it was announced that Wheeler had quit her role after five years on the show as she felt the time was right to try something new. Wheeler left in March 2006 and returned 18 months later in September 2007. In 2015, Wheeler became pregnant and took maternity leave. Nicola left screens in March 2015 and returned eight months later in November 2015.
Nicola won "Best Bitch" at The British Soap Awards 2006 Nicola was also nominated for "Best Villain" at the British Soap Awards in 2002, 2008 and 2009. She was nominated for the All About Soap "Bad Girl" award in 2009 and was nominated for most shocking baby plot in 2010. She was nominated for Inside Soap's "Bad Bitch" award in 2009 In a poll run by website Digital Spy, 95% of voters were on Nicola's side of Jimmy's amnesia storyline
In September 2012, Kate White of Inside Soap praised Nicola's comedic reactions and named her 'our hero', "We love Nicola having a front-row seat at Home Farm Estates. Her comedy reactions make all that business vastly more bearable."