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Milo Murphy's Law (previously titled Mikey Murphy's Law) is an American animated television series from the creators of Phineas and Ferb, Dan Povenmire and Jeff "Swampy" Marsh, which premiered on October 3, 2016 on Disney XD. The series revolves around the title character, Milo Murphy, who is a descendant of Edward A. Murphy Jr., the namesake of Murphy's law, which states that anything that can go wrong, will go wrong.
On February 28, 2017, the show was renewed for a second season.
Main
"Weird Al" Yankovic as Milo Murphy, the title character of the series. He has a reputation for having extreme misfortune, but he is always optimistic and finds ways to overcome it. He carries a backpack with him that always seems to have what he needs for any given situation. It was given to him by his old babysitter, Veronica, who was the only one able to handle Murphy's Law.
Sabrina Carpenter as Melissa Chase, a long-time friend of Milo's who likes to hang out with him despite his bad luck. Her father is the local fire chief. She has had a secret fear of rollercoasters since one nearly fell on her.
Mekai Curtis as Zack Underwood, the new kid in Swamp City who becomes best friends with Milo and Melissa and sticks by Milo even though he is a jinx. He is on the football team. He was once the lead singer of a boy band called "The Lumberzacks". He also has a fear of goldfish.
Recurring
Dan Povenmire and Jeff "Swampy" Marsh as Vinnie Dakota and Balthazar Cavendish, respectively, time travelers from the future, given the assignment to prevent the extinction of the pistachio. They are considered a joke by fellow time agents because their job is considered inconsequential and was only given to them because their boss likes pistachios. A semi-recurring gag involves Milo attempting to purchase pistachios from them and his bad luck causing them to lose their pistachios.
Christian Slater as Elliot Decker, the school crossing guard and self-described "Safety Czar". He makes it his mission to protect the city from Milo, and constantly hinders Milo and the gang, particularly Milo. He even goes so far as to have a "STOP" sign with "MILO" on the other side.
Vanessa Williams as Eileen Underwood, Zack's mother, and a surgeon.
Phil LaMarr as Marcus Underwood, Zack's father. He didn't believe in Murphy's Law until he and Zack joined Milo and his father on a fishing trip.
Sarah Chalke as Mrs. Murawski, the science teacher of Jefferson County Middle School. She harbors an unhealthy affection towards her desk.
Jemaine Clement as Orton Mahlson, an actor playing the role of Doctor Zone the main character of the eponymous show within a show. He is based on the titular character from Doctor Who, as he travels through time.
Mackenzie Phillips as Elizabeth Milder, the principal of Jefferson County Middle School.
Chrissie Fit as Amanda Lopez, a student in Milo's class who is a perfectionist. It is hinted in "Smooth Opera-tor" that Milo has a crush on her.
Ming-Na Wen as Savannah, an attractive time travel agent who Vinnie has a crush on.
Vincent Martella as Bradley Nicholson, a pessimistic but arrogant student who is jealous of the attention Milo always gets. In "Sunny Side Up", it is hinted that he has a crush on Melissa; this continues through other episodes, though he seems insecure about his affection and lets Melissa's friendship with Milo deter him.
Diedrich Bader as Martin Murphy, Milo's father. Just like his son, he has extreme misfortune. He works as the Swamp City Safety Inspector, mostly due to the fact that when he's around, safety contingencies are pushed to the limit.
Pamela Adlon as Brigette Murphy, Milo's mother, and an architect.
Kate Micucci as Sara Murphy, Milo's older sister and fellow Dr. Zone fan who loves her brother despite his recurring bad luck.
Dee Bradley Baker as Deogee, Milo's dog. He regularly follows Milo, who keeps telling him to go home as he is almost always not allowed to be wherever Milo is at the moment. His name is pronounced "D-O-G," as if spelling out the word "dog."
Greg Cipes as Mort Schaeffer, a burly-looking student in Milo's class. He is Bradley's friend, but is annoyed over Bradley's arrogance and tends to be civil with Milo.
Laraine Newman as Ms. White, another high school teacher.
Mark Hamill as Mr. Block, Cavendish and Dakota's superior.
Scott Peterson as Scott, a pipe maker who has been stuck underground for years.
Django Marsh as Chad, a classmate of Milo's who is convinced that Mr. Drako is a vampire.
Episodes
The first season will contain 21 half-hours.
Broadcast
The first episode of the show was released for free at Google Play, iTunes Store and Amazon on September 19, 2016, followed by its official premiere on October 3, 2016 on Disney XD in the United States. The show premiered on Disney XD in Canada on October 17, 2016 and in Latin America on January 28, 2017 (previewed on December 31, 2016 on Disney XD and January 1, 2017 on Disney Channel). It premiered on Disney XD and Disney Channel in the United Kingdom as a special preview in December 2016 (its official premiere is early 2017) and on Disney XD in Spain on January 9, 2017. The show premiered on Asian territories such as Disney Channel in Japan on February 13, 2017 and Southeast Asia on February 10, 2017. In France, it will air on Disney XD starting on February 20, 2017 under the name "La Loi de Milo Murphy". The show will begin airing on Disney Channel in Spain and Portugal on April 1, 2017.