Entrez 2847 | Ensembl ENSG00000128285 | |
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Aliases MCHR1, GPR24, MCH-1R, MCH1R, SLC-1, SLC1, melanin concentrating hormone receptor 1 External IDs MGI: 2180756 HomoloGene: 21097 GeneCards: MCHR1 |
Melanin-concentrating hormone receptor 1, also known as MCH1, is one of the melanin-concentrating hormone receptors found in all mammals.
Contents
The protein encoded by this gene, a member of the G protein-coupled receptor family 1, is an integral plasma membrane protein which binds melanin-concentrating hormone. The encoded protein can inhibit cAMP accumulation and stimulate intracellular calcium flux, and is probably involved in the neuronal regulation of food consumption. Although structurally similar to somatostatin receptors, this protein does not seem to bind somatostatin.
Function
MCH1 is thought to have a number of functions including in the regulation of appetite, and in stress, anxiety and depression.
Agonists
Antagonists
References
Melanin-concentrating hormone receptor 1 Wikipedia(Text) CC BY-SA