Entrez 4174 | Ensembl ENSG00000100297 | |
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Aliases MCM5, CDC46, P1-CDC46, minichromosome maintenance complex component 5 External IDs MGI: 103197 HomoloGene: 4904 GeneCards: MCM5 | ||
DNA replication licensing factor MCM5 is a protein that in humans is encoded by the MCM5 gene.
Contents
Function
The protein encoded by this gene is structurally very similar to the CDC46 protein from S. cerevisiae, a protein involved in the initiation of DNA replication. The encoded protein is a member of the MCM family of chromatin-binding proteins and can interact with at least two other members of this family. The encoded protein is upregulated in the transition from the G0 to G1/S phase of the cell cycle and may actively participate in cell cycle regulation.
Interactions
MCM5 has been shown to interact with:
References
MCM5 Wikipedia(Text) CC BY-SA