Mr McCarthy made over 30 guest star appearances on television shows such as "Elementary", " The Good Wife", "Madam Secretary",Law & Order: Special Victims Unit, Ed, Designing Women, Cheers, Freddy's Nightmares, Matlock, and In the Heat of the Night. McCarthy played the father of Wayne (Freddy Geiger) on the short lived CBS show Love Monkey. McCarthy played Albert Schweitzer in Albert Schweitzer: Called to Africa, a TV film on PBS.
David Letterman created a running bit for Mr. McCarthy who played a typically full of it politician who, in the middle of primary season, announces on The Late Show that he will run for President of the United States.
He has made guest appearances on two Star Trek series; on Star Trek: The Next Generation, he appeared in the season 3 episode "The Hunted" as Roga Danar, and in the pilot episode of Star Trek: Voyager entitled "Caretaker" as chief medical officer Dr. Fitzgerald of the USS Voyager who was killed in the premiere episode.
Mr McCarthy was chosen by the great Chuck Jones to be the voice of Michigan J. Frog in his 1994 "Another Froggy Evening", a sequel to the original 1955 cartoon "One Froggy Evening". Jeff McCarthy went on to voice Michigan J. Frog, "spokesphibian" for the WB Television Network.
Mr McCarthy has played various roles in films including "Starting Out In the Evening" with Frank Langella, "Consent" opposite Kate Burton. "Robocop 2" playing Holtzgang, the lawyer representing the company that built Robocop, "Eve of Destruction", "Rapid Fire", "Cliffhanger".
Working with his brother, Jim McCarthy in 2016 - Jeff wrote, directed and edited "KEEPSAKE", a short film featuring his daughter, the actress Juliet Perrell McCarthy. https://vimeo.com/194950286
In theatre, McCarthy debuted on Broadway in 1983, playing opposite Anthony Quinn in Zorba. He went on to play Bob Freelander in the ill-fated Smile, the following year. In 2001, McCarthy created the role of Officer Lockstock in the original cast of the Broadway musical Urinetown, drama desk nomination. He played the Beast in the Broadway production of Beauty and the Beast, and Terry in the original cast of Side Show. In 2004, McCarthy reprised his role as the Beast in Beauty and the Beast for eight weeks. He played Dubhdara in the recent musical The Pirate Queen. In 2008, 2009 and 2011, McCarthy played Billy Flynn in Chicago, the long-running Broadway revival. In 2012, McCarthy played the title role in the stage version of How the Grinch Stole Christmas! at Madison Square Garden. Most recently, McCarthy created the title character in Jeffrey Sweet's Kunstler about the radical civil rights attorney, William Kunstler; GPR records recorded the performance and will be available on various sites on the internet.Robocop 2 (1990) - Holzgang
Eve of Destruction (1991) - Young Bill Simmons
Rapid Fire (1992) - Agent Anderson
Cliffhanger (1993) - Pilot
Starting Out in the Evening (2007) - Charles
Consent (2010) - Mark