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HLA-DR5 (DR5) is a broad-antigen serotype that is further split into HLA-DR11 and HLA-DR12 antigen serotypes.
Contents
Serology
With the exception of a few DRB1* alleles the reactivity of DR5 is relatively poor.
Disease associations
DR5 is associated with persistent generalized lymphadenopathy (PGL) and Kaposi sarcoma in AIDS, juvenile rheumatoid arthritis, pernicious anemia, Hashimoto's thyroiditis, mycosis fungoides, polyglandular deficiency syndrome, systemic sclerosis, childhood epilepsy, early-onset alopecia areata, short-ragweed Ra6 allergy, primary antiphospholipid syndrome, and increased longevity in the Dutch
Genetic linkage
HLA-DR5 reactive gene products are linked to serology of HLA-DRB3 (HLA-DR52).
References
HLA-DR5 Wikipedia(Text) CC BY-SA