Structure αβ heterodimer Subtype allele | allele Available structures | |
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Subunits HLA-A*4301, β2-microglobulin | ||
HLA-A43 (A43) is a human leukocyte antigen serotype within HLA-A serotype group. The serotype is determined by the antibody recognition of α43 subset of HLA-A α-chains. For A43, the alpha "A" chain are encoded by the HLA-A*43 allele group and the β-chain are encoded by B2M locus. This group currently is dominated by A*4301. A43 and A*43 are almost synonymous in meaning. A43 is a split antigen of the broad antigen serotype A10. A43 is a sister serotype of A25, A26, A34, and A66.
Contents
A43 is more common in Africa and SouthWest Asia. A43 is believed to have been formed by a single gene conversion between another HLA-A and the A*2601 allele..
Serotype
A43 serotyping is poor.
References
References
HLA-A43 Wikipedia(Text) CC BY-SA