Rahul Sharma (Editor)

HLA A26

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Structure
  
αβ heterodimer

Subtype
  
allele

Older names
  
A10

allele
  
Available structures

HLA-A26

Protein
  
transmembrane receptor/ligand

Subunits
  
HLA-A*2601, β2-microglobulin

HLA-A26 (A26) is a human leukocyte antigen serotype within HLA-A serotype group. The serotype is determined by the antibody recognition of α26 subset of HLA-A α-chains. For A26, the alpha "A" chain are encoded by the HLA-A*26 allele group and the β-chain are encoded by B2M locus. This group currently is dominated by A*2601. A26 and A*26 are almost synonymous in meaning. A26 is a split antigen of the broad antigen serotype A10. A26 is a sister serotype of A25, A34, A43, and A66.

Contents

A26 is more common in West Pacific Rim (Taiwan to Hokkaido).

Serotype

A26 reasonably good serotyping with no overt false recognition..

Disease associations

A26 Serotype is associated with adult T-cell leukemia in Japanese.

References

HLA-A26 Wikipedia


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