Puneet Varma (Editor)

Gene Designer

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Developer(s)
  
DNA2.0

Operating system
  
Windows, macOS, Linux

Development status
  
Active

Platform
  
x86, x86-64

Initial release
  
2006; 11 years ago (2006)

Stable release
  
2.01.191 / October 9, 2015; 16 months ago (2015-10-09)

Gene Designer is a computer software package for bioinformatics. It is used by molecular biologists from academia, government, and the pharmaceutical, chemical, agricultural, and biotechnology industries to design, clone, and validate genetic sequences. It is proprietary software, released as freeware needing registration.

Contents

Features

Gene Designer enables molecular biologists to manage the full gene design process in one application, using a range of design tools.

  • Algorithms for in silico cloning, codon optimization, back translation, and primer design
  • Graphic molecular View to display, annotate, and edit constructs
  • Customizable database to store, manage, and track genetic elements, genes, and constructs
  • Drag and drop interface to move sequence elements within or between constructs (patented feature)
  • Search feature for sequence motifs, restriction sites, and open reading frames
  • Codon optimize for recombinant protein production in any organism using multiple algorithms
  • Remove or add restriction sites or other sequence motifs
  • Recode open reading frames
  • Check translation frames and fusion junctions
  • Design oligonucleotides to sequence primers, includes a real time melting point calculator
  • Cloning tool with drag and drop ability to cut, combine, and clone insert and vector

    • Educator and student use

    This free software has been incorporated into classroom and lab curricula for synthetic biology, systems biology, bioengineering, and bioinformatics. Students create and complete projects which manage the full gene design process in one application, using a range of design tools.

    Examples of use in curricula:

  • Synthetic Biophotonics Course; Utah State University, College of Engineering
  • Lab Project using Gene Designer 2.0
  • Systems Biology Lesson Overview
  • Synthetic Biology Lesson Overview
  • Student Projects

    • Other software

  • Clone manager
  • Geneious
  • MacVector
  • UGENE
  • Vector NTI

    • References

    Gene Designer Wikipedia
    (Text) CC BY-SA