Alex Whitman (Matthew Perry) is an architect from New York City who is sent to Las Vegas to supervise the construction of a nightclub that his firm has been hired to build. Alex is a strait-laced WASP-ish type who, while researching possible menus items for the new nightclub, he meets Isabel Fuentes (Salma Hayek), a free-spirited Mexican-American photographer. Alex and Isabel are overtaken by lust at first sight and end up spending the night together; however, their immediate attraction doesn't last in the cold light of day, and they don't see each other for another three months.
When they do meet again, it's because Isabel has some interesting news for Alex: she's pregnant with his child. Isabel decide to keep and raise the child. Alex suddenly realizes he didn't know Isabel is all he ever wanted. He proposes and they quickly get married (with an Elvis impersonator serving as witness), but after Isabel meets Alex's mom (Jill Clayburgh) and Alex is confronted by Isabel's father (Tomas Milian), both start to wonder if "doing the right thing" was just that, especially as Alex tries to balance his career in New York with Isabel's desire to continue working in Nevada.
They end up divorced on the night of their daughter's birth, but soon remarry with both of their families present.
Matthew Perry as Alex Whitman
Salma Hayek as Isabel Fuentes-Whitman
Jon Tenney as Jeff
Carlos Gómez as Chuy
Tomás Milián as Tomas Fuentes
Siobhan Fallon as Lainie
John Bennett Perry as Richard Whitman
Stanley DeSantis as Judd Marshall
Suzanne Snyder as Cathy Stewart
Anne Betancourt as Amalia Fuentes
Jill Clayburgh as Nan Whitman
Garret Davis as Stan
Annie Combs as Dr. Lisa Barnes, Ob-Gyn
Annetta Ray as minister performing marriage
The following list of titles represents the music used in sequence with the movie.
Santa Claus is Comin' to Town - Burl Ives (office Christmas party scene)
Jailhouse Rock - Elvis Presley (Alex gets excited about Las Vegas)
Las Abajeñas - Mariachi Reyes de Aserradero
Two to Tango - Vanessa Daou (one-night stand/morning after)
Para Donde Vas - The Iguanas (playing while Alex follows Isabel in his car, just after she announces she's pregnant)
Ain't That a Kick in the Head - Dean Martin (Elvis impersonator wedding/honeymoon scene)
Linda Guerita - Brave Combo
Si Tu Te Vas - Enrique Iglesias
Mi Tierra - Gloria Estefan
La Virgen de la Macarena - Pérez Prado
Nothing is Permanent - Brave Combo
La Bamba - Mariachi Vargas de Tecalitlán
Los Machetes - Mariachi Vargas de Tecalitlán
Fever - Peggy Lee (Alex's parents leaving Las Vegas scene)
Talk to Me - Wild Orchid ("Boulevard Club" opening night scene)
Naked Eye - Luscious Jackson ("Boulevard Club" opening night scene/Isabel walks out)
I Wonder - Chris Isaak (Isabel on her way to her grandmother's house)
Danke Schoen - Wayne Newton (Alex's "epiphany"/leaving New York)
It's Now or Never - Elvis Presley (Alex on the trail to find Isabel)
Can't Help Falling in Love - Elvis Presley (The "real wedding"/closing credits)
Fools Rush In holds a 33% rating on Rotten Tomatoes.