Harman Patil

Enterobacter

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Kingdom  Bacteria
Order  Enterobacteriales
Scientific name  Enterobacter
Rank  Genus
Phylum  Proteobacteria
Family  Enterobacteriaceae
Higher classification  Enterobacteriaceae
Enterobacter httpsuploadwikimediaorgwikipediacommons77
Lower classifications  Enterobacter cloacae, Enterobacter aerogenes

Proteus enterobacter y citrobacter


Enterobacter is a genus of common Gram-negative, facultatively anaerobic, rod-shaped, non-spore-forming bacteria of the family Enterobacteriaceae. Several strains of these bacteria are pathogenic and cause opportunistic infections in immunocompromised (usually hospitalized) hosts and in those who are on mechanical ventilation. The urinary and respiratory tracts are the most common sites of infection. The genus Enterobacter is a member of the coliform group of bacteria. It does not belong to the fecal coliforms (or thermotolerant coliforms) group of bacteria, unlike Escherichia coli, because it is incapable of growth at 44.5 °C in the presence of bile salts. Some of them showed quorum sensing properties as reported before

Contents

Two clinically important species from this genus are E. aerogenes and E. cloacae.

Enterobacter cloacae


Biochemical characteristics

The genus Enterobacter ferments lactose with gas production during a 48-hour incubation at 35-37 °C in the presence of bile salts and detergents. It is oxidase-negative, indole-negative, and urease-variable.

Treatment

  • Note: Treatment is dependent on local trends of antibiotic resistance.
    1. Cefepime, a fourth-generation cephalosporin from the β-Lactam antibiotic class.
    2. Imipenem (carbapenems) is often the antibiotic of choice.
    3. Aminoglycosides such as amikacin have been found to be very effective, as well.
    4. Quinolones can be an effective alternative.

    Linked to obesity

    A recent study has shown that the presence of Enterobacter cloacae B29 in the gut of a morbidly obese individual may have contributed to the patient’s obesity. Reduction of the bacterial load within the patient’s gut, from 35% E. cloacae B29 to non-detectable levels, was associated with a parallel reduction in endotoxin load in the patient and a concomitant, significant reduction in weight. Furthermore, the same bacterial strain, isolated from the patient, induced obesity and insulin resistance in germfree C57BL/6J mice that were being fed a high-fat diet. The study concludes that E. cloacae B29 may contribute to obesity in its human hosts through an endotoxin-induced, inflammation-mediated mechanism.

    References

    Enterobacter Wikipedia


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