Suvarna Garge

Elbs reaction

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Elbs reaction

The Elbs reaction is an organic reaction describing the pyrolysis of an ortho methyl substituted benzophenone to condensed polyaromatic. The reaction is named after its inventor, the German chemist Karl Elbs also responsible for the Elbs oxidation. The reaction was published in 1884

Contents

Elbs however did not correctly interpret the reaction product due to a lack of knowledge about naphthalene structure.

Scope

The Elbs reaction enables the synthesis of condensed aromatic systems. As already demonstrated by Elbs in 1884 it is possible to obtain anthracene through dehydration. Larger aromatic systems like pentacene are also feasible. This reaction does not take place in a single step but leads first to dihydropentacene that is dehydrogenated in a second step with copper as a catalyst.

The acyl compounds required for this reaction can be obtained through a Friedel-Crafts acylation with aluminum chloride.

Variations

It is also possible to synthesise heterocyclic compounds via the Elbs reaction. In 1956 an Elbs reaction of a thiophene derivative was published. The expected linear product was not obtained due to a change in reaction mechanism after formation of the first intermediate which caused multiple free radical reaction steps.

References

Elbs reaction Wikipedia


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