Species Human Entrez 1643 | Human Mouse Ensembl ENSG00000134574 | |
 | ||
Aliases DDB2, DDBB, UV-XPE, damage specific DNA binding protein 2 External IDs MGI: 1355314 HomoloGene: 83 GeneCards: DDB2 | ||
DNA damage-binding protein 2 is a protein that in humans is encoded by the DDB2 gene.
Contents
Function
DDB2 is the smaller subunit of a heterodimeric protein implicated in the etiology of xeroderma pigmentosum group E. This subunit appears to be required for DNA binding.
Interactions
DDB2 has been shown to interact with CUL4A, CUL4B and DDB1. Also, some researches about DDB2 show a relationship between DDB2 and PARP1.PARP1 as a novel DDB2-associated factor,which may help to recruitment a chromatin-remodeling enzyme,named ALC1.
References
DDB2 Wikipedia(Text) CC BY-SA